The human heart and rat brain IIA Na+ channels interact with different molecular regions of the beta1 subunit
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Sodium channel β1 subunit mutations associated with Brugada syndrome and cardiac conduction disease in humansMutations in sodium channel β1- and β2-subunits associated with atrial fibrillationSodium channel beta1 subunit-mediated modulation of Nav1.2 currents and cell surface density is dependent on interactions with contactin and ankyrinCardiac Na Channels: Structure to FunctionMultiple loss-of-function mechanisms contribute to SCN5A-related familial sick sinus syndrome.Identification of Navβ1 residues involved in the modulation of the sodium channel Nav1.4.Regulation of Nav1.6 and Nav1.8 peripheral nerve Na+ channels by auxiliary β-subunits.Differential expression of sodium channel β subunits in dorsal root ganglion sensory neurons.Post-translational modifications of voltage-gated sodium channels in chronic pain syndromesSodium channel inactivation: molecular determinants and modulation.Differential sialylation modulates voltage-gated Na+ channel gating throughout the developing myocardiumConotoxins targeting neuronal voltage-gated sodium channel subtypes: potential analgesics?Binary architecture of the Nav1.2-β2 signaling complexCo-expression of Na(V)β subunits alters the kinetics of inhibition of voltage-gated sodium channels by pore-blocking μ-conotoxins.β1- and β3- voltage-gated sodium channel subunits modulate cell surface expression and glycosylation of Nav1.7 in HEK293 cells.BACE1 regulates voltage-gated sodium channels and neuronal activity.Voltage-gated sodium channels: biophysics, pharmacology, and related channelopathies.Voltage-gated sodium channels in the mammalian heart.Functional modulation of voltage-dependent sodium channel expression by wild type and mutated C121W-β1 subunit.The sialic acid component of the beta1 subunit modulates voltage-gated sodium channel function.Distinct domains of the sodium channel beta3-subunit modulate channel-gating kinetics and subcellular location.The intracellular domain of the beta 2 subunit modulates the gating of cardiac Na v 1.5 channels.Modulation of Nav1.5 channel function by an alternatively spliced sequence in the DII/DIII linker region.A naturally occurring amino acid substitution in the voltage-dependent sodium channel selectivity filter affects channel gating.β1 subunit stabilises sodium channel Nav1.7 against mechanical stress.
P2860
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P2860
The human heart and rat brain IIA Na+ channels interact with different molecular regions of the beta1 subunit
description
2002 nî lūn-bûn
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2002年の論文
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2002年学术文章
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2002年学术文章
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name
The human heart and rat brain ...... r regions of the beta1 subunit
@ast
The human heart and rat brain ...... r regions of the beta1 subunit
@en
type
label
The human heart and rat brain ...... r regions of the beta1 subunit
@ast
The human heart and rat brain ...... r regions of the beta1 subunit
@en
prefLabel
The human heart and rat brain ...... r regions of the beta1 subunit
@ast
The human heart and rat brain ...... r regions of the beta1 subunit
@en
P2860
P356
P1476
The human heart and rat brain ...... r regions of the beta1 subunit
@en
P2093
Klaus Benndorf
Thomas Zimmer
P2860
P304
P356
10.1085/JGP.20028703
P577
2002-12-01T00:00:00Z