Hypomethylation of the IL17RC promoter associates with age-related macular degeneration.
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Chronic over-nutrition and dysregulation of GSK3 in diseasesEpigenetics and agingInflammation and its role in age-related macular degenerationMolecular pathology of macrophages and interleukin-17 in age-related macular degenerationGenetic and environmental underpinnings to age-related ocular diseasesEpigenetics and Common Ophthalmic DiseasesDNA methylation landscape of ocular tissue relative to matched peripheral blood.Systemic frequencies of T helper 1 and T helper 17 cells in patients with age-related macular degeneration: A case-control study.SIRT6 is required for normal retinal functionAssociation between aqueous humor and vitreous fluid levels of Th17 cell-related cytokines in patients with proliferative diabetic retinopathy.Immune responses in age-related macular degeneration and a possible long-term therapeutic strategy for preventionOverexpression of IL-17RC associated with ocular sarcoidosis.Insensitivity of PI3K/Akt/GSK3 signaling in peripheral blood mononuclear cells of age-related macular degeneration patients.Altered bioenergetics and enhanced resistance to oxidative stress in human retinal pigment epithelial cells from donors with age-related macular degenerationOverstimulation can create health problems due to increases in PI3K/Akt/GSK3 insensitivity and GSK3 activity.Developments in Ocular Genetics: 2013 Annual Reviewγδ T cells as a major source of IL-17 production during age-dependent RPE degeneration.Inflammation and Cell Death in Age-Related Macular Degeneration: An Immunopathological and Ultrastructural Model.T cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degenerationInterleukin-17 retinotoxicity is prevented by gene transfer of a soluble interleukin-17 receptor acting as a cytokine blocker: implications for age-related macular degeneration.Vision from next generation sequencing: multi-dimensional genome-wide analysis for producing gene regulatory networks underlying retinal development, aging and diseaseConnecting the innate and adaptive immune responses in mouse choroidal neovascularization via the anaphylatoxin C5a and γδT-cells.Responses of Multipotent Retinal Stem Cells to IL-1β, IL-18, or IL-17Epigenetic Regulation of Werner Syndrome Gene in Age-Related Cataract.Differential DNA methylation identified in the blood and retina of AMD patients.Functional single nucleotide polymorphism in IL-17A 3' untranslated region is targeted by miR-4480 in vitro and may be associated with age-related macular degeneration.Epigenetic Mechanisms of the Aging Human Retina.Review: Epigenetic mechanisms in ocular disease.Epigenetics in ocular diseases.The role of the immune response in age-related macular degenerationGenetic and Epigenetic Regulation in Age-related Macular Degeneration.Idiopathic Choroidal Neovascularization: Intraocular Inflammatory Cytokines and the Effect of Intravitreal Ranibizumab Treatment.Aging is not a disease: distinguishing age-related macular degeneration from aging.Pigment epithelium-derived factor reduces apoptosis and pro-inflammatory cytokine gene expression in a murine model of focal retinal degeneration.Hypomethylation of the IL17RC promoter in peripheral blood leukocytes is not a hallmark of age-related macular degeneration.Small-Magnitude Effect Sizes in Epigenetic End Points are Important in Children's Environmental Health Studies: The Children's Environmental Health and Disease Prevention Research Center's Epigenetics Working Group.How genetic studies have advanced our understanding of age-related macular degeneration and their impact on patient care: a review.Twin studies in inherited eye disease.Epigenetics and ocular diseases: from basic biology to clinical study.Translating the ENCyclopedia Of DNA Elements Project findings to the clinic: ENCODE's implications for eye disease.
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P2860
Hypomethylation of the IL17RC promoter associates with age-related macular degeneration.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Hypomethylation of the IL17RC promoter associates with age-related macular degeneration.
@ast
Hypomethylation of the IL17RC promoter associates with age-related macular degeneration.
@en
type
label
Hypomethylation of the IL17RC promoter associates with age-related macular degeneration.
@ast
Hypomethylation of the IL17RC promoter associates with age-related macular degeneration.
@en
prefLabel
Hypomethylation of the IL17RC promoter associates with age-related macular degeneration.
@ast
Hypomethylation of the IL17RC promoter associates with age-related macular degeneration.
@en
P2093
P2860
P50
P1433
P1476
Hypomethylation of the IL17RC promoter associates with age-related macular degeneration.
@en
P2093
Baoying Liu
Catherine Meyerle
Defen Shen
Diamond Ling
Frederick L Ferris
J Philip McCoy
Michael L Klein
Peter J Francis
P2860
P304
P356
10.1016/J.CELREP.2012.10.013
P50
P577
2012-11-21T00:00:00Z