Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels
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For robust big data analyses: a collection of 150 important pro-metastatic geneseIF5A facilitates translation termination globally and promotes the elongation of many non polyproline-specific tripeptide sequencesGlobal quantitative proteomics reveal up-regulation of endoplasmic reticulum stress response proteins upon depletion of eIF5A in HeLa cells.Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication.ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth.eIF5A-PEAK1 Signaling Regulates YAP1/TAZ Protein Expression and Pancreatic Cancer Cell Growth.The hypusine cascade promotes cancer progression and metastasis through the regulation of RhoA in squamous cell carcinoma.Targeting the polyamine-hypusine circuit for the prevention and treatment of cancer.Blocking Modification of Eukaryotic Initiation 5A2 Antagonizes Cervical Carcinoma via Inhibition of RhoA/ROCK Signal Transduction Pathway.Evolutionary conserved role of eukaryotic translation factor eIF5A in the regulation of actin-nucleating formins.Functional Changes in the Gut Microbiome Contribute to Transforming Growth Factor β-Deficient Colon Cancer.Regulation of gene expression by translation factor eIF5A: Hypusine-modified eIF5A enhances nonsense-mediated mRNA decay in human cells.An overview of polyamine metabolism in pancreatic ductal adenocarcinoma.KRAS oncoprotein expression is regulated by a self-governing eIF5A-PEAK1 feed-forward regulatory loop.Hypusination of eIF5A as a Target for Antiviral Therapy.
P2860
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P2860
Eukaryotic Translation Initiation Factor 5A (EIF5A) Regulates Pancreatic Cancer Metastasis by Modulating RhoA and Rho-associated Kinase (ROCK) Protein Expression Levels
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2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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name
Eukaryotic Translation Initiat ...... OCK) Protein Expression Levels
@ast
Eukaryotic Translation Initiat ...... OCK) Protein Expression Levels
@en
type
label
Eukaryotic Translation Initiat ...... OCK) Protein Expression Levels
@ast
Eukaryotic Translation Initiat ...... OCK) Protein Expression Levels
@en
prefLabel
Eukaryotic Translation Initiat ...... OCK) Protein Expression Levels
@ast
Eukaryotic Translation Initiat ...... OCK) Protein Expression Levels
@en
P2093
P2860
P356
P1476
Eukaryotic Translation Initiat ...... OCK) Protein Expression Levels
@en
P2093
Jan Strnadel
Ken Fujimura
Meghan Wyse
Richard Klemke
Sunkyu Choi
Tracy Wright
P2860
P304
29907-29919
P356
10.1074/JBC.M115.687418
P407
P577
2015-10-19T00:00:00Z