The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition - Wikidata - awgldk - TriplyDB

The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition

The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition

http://www.wikidata.org/entity/Q36445182

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Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9 SLC26A9 is a constitutively active, CFTR-regulated anion conductance in human bronchial epithelia Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients The epithelial anion transporter pendrin is induced by allergy and rhinovirus infection, regulates airway surface liquid, and increases airway reactivity and inflammation in an asthma model Epithelial Anion Transport as Modulator of Chemokine Signaling Epithelial Electrolyte Transport Physiology and the Gasotransmitter Hydrogen Sulfide Mucociliary dysfunction in HIV and smoked substance abuse Epithelial Sodium and Chloride Channels and Asthma Microscale imaging of cilia-driven fluid flow Mucociliary clearance: pathophysiological aspects Method for quantitative study of airway functional microanatomy using micro-optical coherence tomography Airway hydration and COPD Forces applied by cilia measured on explants from mucociliary tissue.Restoration of mucociliary transport in the fluid-depleted trachea by surface-active instillates Mechanistic model of Rothia mucilaginosa adaptation toward persistence in the CF lung, based on a genome reconstructed from metagenomic data Effect of epithelium ATP release on cyclic pressure-induced airway mucus secretion.Smoking is associated with shortened airway cilia PLUNC is a novel airway surfactant protein with anti-biofilm activity.Little Cigars are More Toxic than Cigarettes and Uniquely Change the Airway Gene and Protein Expression.Airway surface liquid depth imaged by surface laser reflectance microscopy.β1-Integrin Accumulates in Cystic Fibrosis Luminal Airway Epithelial Membranes and Decreases Sphingosine, Promoting Bacterial Infections Normal and cystic fibrosis airway surface liquid homeostasis. The effects of phasic shear stress and viral infections Nucleotide release provides a mechanism for airway surface liquid homeostasis Is cystic fibrosis lung disease caused by abnormal ion composition or abnormal volume?Mucus clearance as a primary innate defense mechanism for mammalian airways.Nasal potential difference to detect Na+ channel dysfunction in acute lung injury.Domiciliary humidification improves lung mucociliary clearance in patients with bronchiectasis.Linking increased airway hydration, ciliary beating, and mucociliary clearance through ENaC inhibition Functional apical large conductance, Ca2+-activated, and voltage-dependent K+ channels are required for maintenance of airway surface liquid volume.Hyperviscous airway periciliary and mucous liquid layers in cystic fibrosis measured by confocal fluorescence photobleaching.Vasotocin and vasopressin stimulation of the chloride secretion in the human bronchial epithelial cell line, 16HBE14o-.Transforming growth factor-β1 and cigarette smoke inhibit the ability of β2-agonists to enhance epithelial permeability.Measurement of the airway surface liquid volume with simple light refraction microscopy.Acid and base secretion in freshly excised nasal tissue from cystic fibrosis patients with ΔF508 mutation Automated acquisition and analysis of airway surface liquid height by confocal microscopy Inositol polyphosphate derivative inhibits Na+ transport and improves fluid dynamics in cystic fibrosis airway epithelia.Suppression of adenosine-activated chloride transport by ethanol in airway epithelia A spatial model of fluid recycling in the airways of the lung.Strategic targets of essential host-pathogen interactions.Soluble mediators, not cilia, determine airway surface liquid volume in normal and cystic fibrosis superficial airway epithelia.

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P2860

The relative roles of passive surface forces and active ion transport in the modulation of airway surface liquid volume and composition

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The Journal of General Physiology

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B R Grubb

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C W Davis

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J T Gatzy

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R C Boucher

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R Tarran

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P2860

Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease

Human beta-defensin-1 is a salt-sensitive antibiotic in lung that is inactivated in cystic fibrosis

Osmotic water permeabilities of cultured, well-differentiated normal and cystic fibrosis airway epithelia

Cystic fibrosis and the salt controversy.

Molecular insights into the physiology of the 'thin film' of airway surface liquid.

Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid.

Morphometric aspects of ciliary distribution and ciliogenesis in human nasal epithelium.

Ion composition of airway surface liquid of patients with cystic fibrosis as compared with normal and disease-control subjects.

Coordinated clearance of periciliary liquid and mucus from airway surfaces.

Direct determination of volume- and time-dependence of alveolar surface tension in excised lungs.

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