Cocrystal Solubilization in Biorelevant Media and its Prediction from Drug Solubilization

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How cocrystals of weakly basic drugs and acidic coformers might modulate solubility and stability.Cocrystals to facilitate delivery of poorly soluble compounds beyond-rule-of-5 Engineering Cocrystals of PoorlyWater-Soluble Drugs to Enhance Dissolution in Aqueous Medium

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P2860

Cocrystal Solubilization in Biorelevant Media and its Prediction from Drug Solubilization

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2015年学术文章

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2015年学术文章

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Cocrystal Solubilization in Biorelevant Media and its Prediction from Drug Solubilization

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Cocrystal Solubilization in Biorelevant Media and its Prediction from Drug Solubilization

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Cocrystal Solubilization in Biorelevant Media and its Prediction from Drug Solubilization

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Cocrystal Solubilization in Biorelevant Media and its Prediction from Drug Solubilization

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Cocrystal Solubilization in Biorelevant Media and its Prediction from Drug Solubilization

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Cocrystal Solubilization in Biorelevant Media and its Prediction from Drug Solubilization

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P1476

Cocrystal Solubilization in Biorelevant Media and its Prediction from Drug Solubilization

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P2093

Lilly Roy

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Maya P Lipert

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Naír Rodríguez-Hornedo

http://www.w3.org/2001/XMLSchema#string

Scott L Childs

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P2860

The co-crystal approach to improve the exposure of a water-insoluble compound: AMG 517 sorbic acid co-crystal characterization and pharmacokinetics.

Use of a glutaric acid cocrystal to improve oral bioavailability of a low solubility API.

Effect of food on the relative bioavailability of two oral formulations of posaconazole in healthy adults.

Cocrystal Transition Points: Role of Cocrystal Solubility, Drug Solubility, and Solubilizing Agents.

The effects of food on drug bioavailability.

Coformer selection in pharmaceutical cocrystal development: a case study of a meloxicam aspirin cocrystal that exhibits enhanced solubility and pharmacokinetics.

Forecasting the oral absorption behavior of poorly soluble weak bases using solubility and dissolution studies in biorelevant media.

Physiochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH.

Bioavailability of indomethacin-saccharin cocrystals.

Effect of liquid volume and food intake on the absolute bioavailability of danazol, a poorly soluble drug.

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scholarly article

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10.1002/JPS.24640

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Cocrystal Solubilization in Biorelevant Media and its Prediction from Drug Solubilization

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P2860

P2860

Cocrystal Solubilization in Biorelevant Media and its Prediction from Drug Solubilization

description

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P1433

P1476

P2093

P2860

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P407

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P698

P932

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P1476

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P2860

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P31

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P433

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P577

P698

P932