Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform
about
Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilizationRole of phosphoinositide 3-kinase beta in glycoprotein VI-mediated Akt activation in platelets.A novel small molecule 1,2,3,4,6-penta-O-galloyl-α-D-glucopyranose mimics the antiplatelet actions of insulinRole of insulin-like growth factor 1 in stent thrombosis under effective dual antiplatelet therapy.Expression of regulatory platelet microRNAs in patients with sickle cell diseaseLoss of the insulin receptor in murine megakaryocytes/platelets causes thrombocytosis and alterations in IGF signalling.Circulating primers enhance platelet function and induce resistance to antiplatelet therapy.Role of IGF-1 in glucose regulation and cardiovascular disease.Platelet defects in congenital variant of Rett syndrome patients with FOXG1 mutations or reduced expression due to a position effect at 14q12.Akt signaling in platelets and thrombosis.Chemokine CXCL12 uses CXCR4 and a signaling core formed by bifunctional Akt, extracellular signal-regulated kinase (ERK)1/2, and mammalian target of rapamycin complex 1 (mTORC1) proteins to control chemotaxis and survival simultaneously in mature deCholinergic receptor pathways involved in apoptosis, cell proliferation and neuronal differentiation.Non-redundant roles of phosphoinositide 3-kinase isoforms alpha and beta in glycoprotein VI-induced platelet signaling and thrombus formation.Role of phosphoinositide 3-kinase beta in platelet aggregation and thromboxane A2 generation mediated by Gi signalling pathways.Impact of atrial fibrillation on platelet gene expression.Enhanced platelet activity and thrombosis in a murine model of type I diabetes are partially insulin-like growth factor 1-dependent and phosphoinositide 3-kinase-dependent.
P2860
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P2860
Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
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2007年學術文章
@zh-hant
name
Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform
@ast
Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform
@en
type
label
Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform
@ast
Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform
@en
prefLabel
Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform
@ast
Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform
@en
P2093
P2860
P1433
P1476
Insulin-like growth factor-1 regulates platelet activation through PI3-Kalpha isoform
@en
P2093
Analia Garcia
Satya P Kunapuli
Soochong Kim
P2860
P304
P356
10.1182/BLOOD-2007-03-080804
P407
P577
2007-09-07T00:00:00Z