Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8) - Wikidata - awgldk - TriplyDB

Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8)

Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8)

http://www.wikidata.org/entity/Q36447920

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Antioxidants of Edible Mushrooms Role of calcium-dependent protein kinases in chronic myeloid leukemia: combined effects of PKC and BCR-ABL signaling on cellular alterations during leukemia development Childhood acute myeloid leukaemia Quantitative phenotyping-based in vivo chemical screening in a zebrafish model of leukemia stem cell xenotransplantation Inhibition of glioblastoma growth by the thiadiazolidinone compound TDZD-8 Small Molecule Inhibitor of CBFβ-RUNX Binding for RUNX Transcription Factor Driven Cancers Deregulation of c-Myc Confers distinct survival requirements for memory B cells, plasma cells, and their progenitors Advances in complex multiparameter flow cytometry technology: Applications in stem cell research.Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data.Cancer stem/progenitor cell active compound 8-quinolinol in combination with paclitaxel achieves an improved cure of breast cancer in the mouse model Cancer stem cell-directed therapies: recent data from the laboratory and clinic.Redox regulation in cancer: a double-edged sword with therapeutic potential.Association of a leukemic stem cell gene expression signature with clinical outcomes in acute myeloid leukemia.Antineoplastic effects of CPPTL via the ROS/JNK pathway in acute myeloid leukemia.Identification and targeting of cancer stem cells.GSK3 is a regulator of RAR-mediated differentiation IL8-CXCR2 pathway inhibition as a therapeutic strategy against MDS and AML stem cells Leukemia stem cells: the root of chronic myeloid leukemia A Hyperactive Signalosome in Acute Myeloid Leukemia Drives Addiction to a Tumor-Specific Hsp90 Species Cytotoxic T cells induce proliferation of chronic myeloid leukemia stem cells by secreting interferon-γ.Preferential eradication of acute myelogenous leukemia stem cells by fenretinide.Hyperpolarized [1-13C]dehydroascorbate MR spectroscopy in a murine model of prostate cancer: comparison with 18F-FDG PET.Reactive oxygen species in eradicating acute myeloid leukemic stem cells Discovery of 1,2,4-thiadiazolidine-3,5-dione analogs that exhibit unusual and selective rapid cell death kinetics against acute myelogenous leukemia cells in culture.Breast cancer stem cells.Redox regulation of cell survival Multispectral imaging of hematopoietic cells: where flow meets morphology.Protein kinase C signalling in leukemia.Alantolactone selectively ablates acute myeloid leukemia stem and progenitor cells.Cancer stem cells: relevance to SCT The BH3-only protein Bim plays a critical role in leukemia cell death triggered by concomitant inhibition of the PI3K/Akt and MEK/ERK1/2 pathways.Glioma stem cell research for the development of immunotherapy.Tumor-initiating and -propagating cells: cells that we would like to identify and control.Acute myeloid leukemia stem cells: seek and destroy.Mitochondrial membrane potential and reactive oxygen species in cancer stem cells.Therapeutic potential of cancer stem cells.Glycogen synthase kinase 3 inhibitors in the next horizon for Alzheimer's disease treatment.Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins Chemoenzymatic synthesis and antileukemic activity of novel C9- and C14-functionalized parthenolide analogs.Can we finally target the leukemic stem cells?

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Rapid and selective death of leukemia stem and progenitor cells induced by the compound 4-benzyl, 2-methyl, 1,2,4-thiadiazolidine, 3,5 dione (TDZD-8)

http://www.wikidata.org/entity/Q36447920

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2007 nî lūn-bûn

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Cheryl A Corbett

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Craig T Jordan

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Fay Young

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Jane L Liesveld

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Josée Hébert

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Monica L Guzman

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Randall M Rossi

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Timothy Bushnell

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Xiaojie Li

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P2860

The sesquiterpene lactone parthenolide induces apoptosis of human acute myelogenous leukemia stem and progenitor cells

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

The interleukin-3 receptor alpha chain is a unique marker for human acute myelogenous leukemia stem cells

Protein kinase C (PKC) family in cancer progression

Atypical protein kinase C iota protects human leukemia cells against drug-induced apoptosis

Missing pieces in the NF-kappaB puzzle

The NCI60 human tumour cell line anticancer drug screen

Isolation of a highly quiescent subpopulation of primitive leukemic cells in chronic myeloid leukemia.

Detection, isolation, and stimulation of quiescent primitive leukemic progenitor cells from patients with acute myeloid leukemia (AML).

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