PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo. - Wikidata - awgldk - TriplyDB

PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo.

PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo.

http://www.wikidata.org/entity/Q36453531

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Salinomycin as a drug for targeting human cancer stem cells The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo Optimal treatment and stochastic modeling of heterogeneous tumors Medulloblastoma stem cells: Promising targets in medulloblastoma therapy Radioresistance of Brain Tumors Glioma Stem Cells and Their Microenvironments: Providers of Challenging Therapeutic Targets Harnessing the apoptotic programs in cancer stem-like cells The three-layer concentric model of glioblastoma: cancer stem cells, microenvironmental regulation, and therapeutic implications Twisted tango: brain tumor neurovascular interactions Cytomegalovirus in human brain tumors: Role in pathogenesis and potential treatment options Brain tumor stem cells: Molecular characteristics and their impact on therapy Cancer stem cells and radioresistance Tumor cells positive and negative for the common cancer stem cell markers are capable of initiating tumor growth and generating both progenies MiR-34a targeting of Notch ligand delta-like 1 impairs CD15+/CD133+ tumor-propagating cells and supports neural differentiation in medulloblastoma Targeting stem cells by radiation: From the biological angle to clinical aspects Metastatic colonization by circulating tumour cells Oncolytic viruses against cancer stem cells: A promising approach for gastrointestinal cancer Imaging and treating tumor vasculature with targeted radiolabeled carbon nanotubes Regulation of mammary stem/progenitor cells by PTEN/Akt/beta-catenin signaling YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer Acute and fractionated irradiation differentially modulate glioma stem cell division kinetics Identification of OLIG2 as the most specific glioblastoma stem cell marker starting from comparative analysis of data from similar DNA chip microarray platforms.A phase I study of perifosine with temsirolimus for recurrent pediatric solid tumors.Heterozygosity for Pten promotes tumorigenesis in a mouse model of medulloblastoma.Microenvironmental regulation of therapeutic response in cancer The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype.ZEB1 sensitizes lung adenocarcinoma to metastasis suppression by PI3K antagonism.A proposed quantitative index for assessing the potential contribution of reprogramming to cancer stem cell kinetics.Epiregulin enhances tumorigenicity by activating the ERK/MAPK pathway in glioblastoma.A phase I study of single-agent perifosine for recurrent or refractory pediatric CNS and solid tumors ABC transporters in CSCs membranes as a novel target for treating tumor relapse.In vitro and in vivo inhibition of neuroblastoma tumor cell growth by AKT inhibitor perifosine Integrated analysis of miRNA and mRNA expression in childhood medulloblastoma compared with neural stem cells Clinically relevant doses of chemotherapy agents reversibly block formation of glioblastoma neurospheres.Most human non-GCIMP glioblastoma subtypes evolve from a common proneural-like precursor glioma Hypoxia increases the expression of stem-cell markers and promotes clonogenicity in glioblastoma neurospheres Epigenetic states of cells of origin and tumor evolution drive tumor-initiating cell phenotype and tumor heterogeneity.Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors.Therapy targets in glioblastoma and cancer stem cells: lessons from haematopoietic neoplasms.

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P2860

PI3K pathway regulates survival of cancer stem cells residing in the perivascular niche following radiation in medulloblastoma in vivo.

http://www.wikidata.org/entity/Q36453531

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2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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PI3K pathway regulates surviva ...... on in medulloblastoma in vivo.

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PI3K pathway regulates surviva ...... on in medulloblastoma in vivo.

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PI3K pathway regulates surviva ...... on in medulloblastoma in vivo.

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PI3K pathway regulates surviva ...... on in medulloblastoma in vivo.

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PI3K pathway regulates surviva ...... on in medulloblastoma in vivo.

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Dolores Hambardzumyan

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Eric C Holland

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Katia Manova-Todorova

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Marc K Rosenblum

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Oren J Becher

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P2860

A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities

Cancerous stem cells can arise from pediatric brain tumors

Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells

Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus

Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

Identification of a cancer stem cell in human brain tumors

Purkinje-cell-derived Sonic hedgehog regulates granule neuron precursor cell proliferation in the developing mouse cerebellum

Identification of neural stem cells in the adult vertebrate brain

A mouse model for medulloblastoma and basal cell nevus syndrome

Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro

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4

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22

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medulloblastoma

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