Vav3 enhances androgen receptor splice variant activity and is critical for castration-resistant prostate cancer growth and survival
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Androgen deprivation-induced senescence promotes outgrowth of androgen-refractory prostate cancer cellsSplice Variants of Androgen Receptor and Prostate CancerVav family exchange factors: an integrated regulatory and functional viewEmerging data on androgen receptor splice variants in prostate cancerAndrogen receptor splice variants and prostate cancer: From bench to bedside.VAV3 mediates resistance to breast cancer endocrine therapy.High-content positional biosensor screening assay for compounds to prevent or disrupt androgen receptor and transcriptional intermediary factor 2 protein-protein interactions.Constitutive activity of the androgen receptor.Identification of novel genes that regulate androgen receptor signaling and growth of androgen-deprived prostate cancer cells.Overexpression of miR-499-5p inhibits non-small cell lung cancer proliferation and metastasis by targeting VAV3.Advances in androgen receptor targeted therapy for prostate cancerPreclinical efficacy of growth hormone-releasing hormone antagonists for androgen-dependent and castration-resistant human prostate cancer.On the origins of the androgen receptor low molecular weight species.Mechanisms of acquired resistance to androgen receptor targeting drugs in castration-resistant prostate cancer.Are androgen receptor variants a substitute for the full-length receptor?Overview on the complexity of androgen receptor-targeted therapy for prostate cancerAndrogen Receptor Coactivators in Regulation of Growth and Differentiation in Prostate Cancer.Reconfiguring the AR-TIF2 Protein-Protein Interaction HCS Assay in Prostate Cancer Cells and Characterizing the Hits from a LOPAC Screen.The microRNA-23b/-27b cluster suppresses prostate cancer metastasis via Huntingtin-interacting protein 1-related.A novel calcium-dependent mechanism of acquired resistance to IGF-1 receptor inhibition in prostate cancer cells.Determinants of Gli2 co-activation of wildtype and naturally truncated androgen receptors.RhoGDIα downregulates androgen receptor signaling in prostate cancer cells.Targeting IGF-IR with ganitumab inhibits tumorigenesis and increases durability of response to androgen-deprivation therapy in VCaP prostate cancer xenografts.Suppression of SPIN1-mediated PI3K-Akt pathway by miR-489 increases chemosensitivity in breast cancer.Targeting constitutively active androgen receptor splice variants in castration resistant prostate cancerAndrogen Receptor Variants Mediate DNA Repair after Prostate Cancer Irradiation.Thioredoxin-1 protects against androgen receptor-induced redox vulnerability in castration-resistant prostate cancer.[Androgen receptor variants in prostate cancer].The clinical value of Vav3 in peripheral blood for predicting lymphatic metastasis of gastric cancer.Aberrant TGF-β Signaling Drives Castration-Resistant Prostate Cancer in a Male Mouse Model of Prostate Tumorigenesis.Targeting AR Variant-Coactivator Interactions to Exploit Prostate Cancer Vulnerabilities.Down-regulation of AR splice variants through XPO1 suppression contributes to the inhibition of prostate cancer progression
P2860
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P2860
Vav3 enhances androgen receptor splice variant activity and is critical for castration-resistant prostate cancer growth and survival
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
@zh-hant
name
Vav3 enhances androgen recepto ...... ate cancer growth and survival
@ast
Vav3 enhances androgen recepto ...... ate cancer growth and survival
@en
type
label
Vav3 enhances androgen recepto ...... ate cancer growth and survival
@ast
Vav3 enhances androgen recepto ...... ate cancer growth and survival
@en
prefLabel
Vav3 enhances androgen recepto ...... ate cancer growth and survival
@ast
Vav3 enhances androgen recepto ...... ate cancer growth and survival
@en
P2093
P2860
P356
P1476
Vav3 enhances androgen recepto ...... ate cancer growth and survival
@en
P2093
Cale D Fahrenholtz
Kerry L Burnstein
Stephanie O Peacock
P2860
P304
P356
10.1210/ME.2012-1165
P577
2012-09-28T00:00:00Z