In vitro biochemical and in vivo biological studies of the uridine 'rescue' of 5-fluorouracil
about
Emergency use of uridine triacetate for the prevention and treatment of life-threatening 5-fluorouracil and capecitabine toxicity.Potent combination therapy for human breast tumors with high doses of 5-fluorouracil: remission and lack of host toxicity.Selective protection by uridine of growth inhibition by 5-fluorouracil (5FU) mediated by 5FU incorporation into RNA, but not the thymidylate synthase mediated growth inhibition by 5FU-leucovorin.Modulation of 5-fluorouracil host-toxicity and chemotherapeutic efficacy against human colon tumors by 5-(Phenylthio)acyclouridine, a uridine phosphorylase inhibitor.Drug resistance, illustration of the complexity of translational research. Steiner Award lecture 1995.Tissue distribution of [18F]-5-fluorouracil in mice: effects of route of administration, strain, tumour and dose.5-(Phenylthio)acyclouridine: a powerful enhancer of oral uridine bioavailability: relevance to chemotherapy with 5-fluorouracil and other uridine rescue regimens.5-Fluorouracil dose escalation enabled with PN401 (triacetyluridine): toxicity reduction and increased antitumor activity in mice.
P2860
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P2860
In vitro biochemical and in vivo biological studies of the uridine 'rescue' of 5-fluorouracil
description
1988 nî lūn-bûn
@nan
1988年の論文
@ja
1988年学术文章
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1988年学术文章
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1988年学术文章
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1988年学术文章
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1988年学术文章
@zh-sg
1988年學術文章
@yue
1988年學術文章
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1988年學術文章
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name
In vitro biochemical and in vi ...... ine 'rescue' of 5-fluorouracil
@ast
In vitro biochemical and in vi ...... ine 'rescue' of 5-fluorouracil
@en
type
label
In vitro biochemical and in vi ...... ine 'rescue' of 5-fluorouracil
@ast
In vitro biochemical and in vi ...... ine 'rescue' of 5-fluorouracil
@en
prefLabel
In vitro biochemical and in vi ...... ine 'rescue' of 5-fluorouracil
@ast
In vitro biochemical and in vi ...... ine 'rescue' of 5-fluorouracil
@en
P2093
P2860
P356
P1476
In vitro biochemical and in vi ...... ine 'rescue' of 5-fluorouracil
@en
P2093
Lankelma J
Laurensse E
van Dijk J
van Groeningen CJ
P2860
P2888
P304
P356
10.1038/BJC.1988.56
P407
P577
1988-03-01T00:00:00Z