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Telomeric protein Pin2/TRF1 induces mitotic entry and apoptosis in cells with short telomeres and is down-regulated in human breast tumorsTelomeric protein Pin2/TRF1 as an important ATM target in response to double strand DNA breaksLong-term cultivation of colorectal carcinoma cells with anti-cancer drugs induces drug resistance and telomere elongation: an in vitro studyHuman Dkk-1, a gene encoding a Wnt antagonist, responds to DNA damage and its overexpression sensitizes brain tumor cells to apoptosis following alkylation damage of DNAEffects of cisplatin on telomerase activity and telomere length in BEL-7404 human hepatoma cellsDNA damage-induced cell cycle checkpoints involve both p53-dependent and -independent pathways: role of telomere repeat binding factor 2Causes of genome instability: the effect of low dose chemical exposures in modern societyDNA repair proteins and telomerase reverse transcriptase in the cochlear lateral wall of cisplatin-treated ratsPlatinum cross-linking of adenines and guanines on the quadruplex structures of the AG3(T2AG3)3 and (T2AG3)4 human telomere sequences in Na+ and K+ solutionsHydroxyl radical-induced apoptosis in human tumor cells is associated with telomere shortening but not telomerase inhibition and caspase activation.Targeting human telomerase for cancer therapeutics.Sodium butyrate enhances the cytotoxic effect of cisplatin by abrogating the cisplatin imposed cell cycle arrest.Formation of cis-diamminedichloroplatinum(II) 1,2-intrastrand cross-links on DNA is flanking-sequence independentUse of an automated capillary DNA sequencer to investigate the interaction of cisplatin with telomeric DNA sequences.Recent advances in the development of telomerase inhibitors for the treatment of cancer.Complex regulation of telomerase activity: implications for cancer therapy.A macrocyclic zinc(II) fluorophore as a detector of apoptosis.DNA interstrand cross-link repair requires replication-fork convergence.Telomere length and genetic variation in telomere maintenance genes in relation to ovarian cancer riskTelomeres, telomerase, and apoptosis.Characterisation of the DNA sequence specificity, cellular toxicity and cross-linking properties of novel bispyridine-based dinuclear platinum complexes.Cisplatin damage: are DNA repair proteins saviors or traitors to the cell?Telomerase and its potential for therapeutic intervention.Heregulin, a new regulator of telomere length in human cellsA human breast cancer model for the study of telomerase inhibitors based on a new biotinylated-primer extension assay.Molecular disruption of RAD50 sensitizes human tumor cells to cisplatin-based chemotherapyCommon Chemical Inductors of Replication Stress: Focus on Cell-Based Studies.Visualization and quantitative analysis of extrachromosomal telomere-repeat DNA in individual human cells by Halo-FISH.Effects of four chemotherapeutic agents, bleomycin, etoposide, cisplatin, and cyclophosphamide, on DNA damage and telomeres in a mouse spermatogonial cell line.Telomerase activity and telomere length in human tumor cells with acquired resistance to anticancer agents.Consequences of telomerase inhibition by BIBR1532 on proliferation and chemosensitivity of chondrosarcoma cell lines.Caspase-dependent apoptosis induced by telomere cleavage and TRF2 loss.Telomerase inhibition and telomere loss in BEL-7404 human hepatoma cells treated with doxorubicin.Effects of three diterpenoids on tumour cell proliferation and telomerase activity.Telomerase in cancer: clinical applications.Dual functional dinuclear platinum complex with selective reactivity towards c-myc G-quadruplex.Telomere dynamics in childhood leukemia and solid tumors: a follow-up study.Selective label-free detection of G-quadruplex structure of human telomere by emission spectral changes in visible-and-NIR region under physiological condition through the FRET of a two-component PPE-SO3−–Pt(ii) complex ensemble with Pt⋯Pt, elePlatination of telomeric sequences and nuclease hypersensitive elements of human c-myc and PDGF-A promoters and their ability to form G-quadruplexesDNA fragment conformations in adducts with Kiteplatin
P2860
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P2860
description
1998 nî lūn-bûn
@nan
1998年の論文
@ja
1998年学术文章
@wuu
1998年学术文章
@zh-cn
1998年学术文章
@zh-hans
1998年学术文章
@zh-my
1998年学术文章
@zh-sg
1998年學術文章
@yue
1998年學術文章
@zh
1998年學術文章
@zh-hant
name
Telomere loss in cells treated with cisplatin
@ast
Telomere loss in cells treated with cisplatin
@en
type
label
Telomere loss in cells treated with cisplatin
@ast
Telomere loss in cells treated with cisplatin
@en
prefLabel
Telomere loss in cells treated with cisplatin
@ast
Telomere loss in cells treated with cisplatin
@en
P2860
P356
P1476
Telomere loss in cells treated with cisplatin
@en
P2093
S J Lippard
T Ishibashi
P2860
P304
P356
10.1073/PNAS.95.8.4219
P407
P577
1998-04-01T00:00:00Z