Immunolocalisation and imaging of small cell cancer xenografts by the IgG2a monoclonal antibody SWA11.
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Results of the central data analysisThe selection of antibodies for targeted therapy of small-cell lung cancer (SCLC) using a human tumour spheroid model to compare the uptake of cluster 1 and cluster w4 antibodies.Selective cytotoxic effects of a ricin A chain immunotoxin made with the monoclonal antibody SWA11 recognising a human small cell lung cancer antigen.Selective immunotherapy of small cell cancer xenografts using 131I-labelled SWA11 antibody.Polyclonal anti-idiotypic antibodies mimicking the small cell lung carcinoma antigen cluster-5A interact with a panel of antibodies and induce specific immune response in animals.Selection of anti-SCLC antibodies for diagnosis of bone marrow metastasis.Expression of a B-cell marker, CD24, on nasopharyngeal carcinoma cells.Lorvotuzumab mertansine, a CD56-targeting antibody-drug conjugate with potent antitumor activity against small cell lung cancer in human xenograft models.Cell binding, internalization and cytotoxic activity of human granzyme B expressed in the yeast Pichia pastoris.The 5'-flanking region of human CD24 gene has cell-type-specific promoter activity in small-cell lung cancer.Potent anti-tumor effects of an anti-CD24 ricin A-chain immunotoxin in vitro and in a disseminated human Burkitt's lymphoma model in SCID mice.Radiation studies on B cell differentiation marker CD24/SCLC Cluster-4 antigen expressing and non-expressing lung cancer cell lines and mouse fibroblasts.Antibodies to the protein core of the small cell lung cancer workshop antigen cluster-w4 and to the leucocyte workshop antigen CD24 recognize the same short protein sequence leucine-alanine-proline.Molecular and biological properties of an abrin A chain immunotoxin designed for therapy of human small cell lung cancer.Cytotoxic activity of ricin A chain immunotoxins recognising cluster 1, w4 and 5A antigens associated with human small cell lung cancer.Monoclonal antibodies defining the cluster-5A small cell lung carcinoma antigen.Biodistribution of a monoclonal antibody (RNL-1) against the neural cell adhesion molecule (NCAM) in athymic mice bearing human small-cell lung-cancer xenografts.Biodistribution and tumour localisation of 131I SWA11 recognising the cluster w4 antigen in patients with small cell lung cancer.Modulation of neuroendocrine surface antigens in oncogene-activated small cell lung cancer lines.
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P2860
Immunolocalisation and imaging of small cell cancer xenografts by the IgG2a monoclonal antibody SWA11.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年学术文章
@wuu
1989年学术文章
@zh-cn
1989年学术文章
@zh-hans
1989年学术文章
@zh-my
1989年学术文章
@zh-sg
1989年學術文章
@yue
1989年學術文章
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1989年學術文章
@zh-hant
name
Immunolocalisation and imaging ...... G2a monoclonal antibody SWA11.
@ast
Immunolocalisation and imaging ...... G2a monoclonal antibody SWA11.
@en
type
label
Immunolocalisation and imaging ...... G2a monoclonal antibody SWA11.
@ast
Immunolocalisation and imaging ...... G2a monoclonal antibody SWA11.
@en
prefLabel
Immunolocalisation and imaging ...... G2a monoclonal antibody SWA11.
@ast
Immunolocalisation and imaging ...... G2a monoclonal antibody SWA11.
@en
P2093
P2860
P356
P1476
Immunolocalisation and imaging ...... G2a monoclonal antibody SWA11.
@en
P2093
P2860
P2888
P304
P356
10.1038/BJC.1989.36
P407
P577
1989-02-01T00:00:00Z