Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina.
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Recent advances in the dark adaptation investigationsRetina, retinol, retinal and the natural history of vitamin A as a light sensorHuman Cellular Retinaldehyde-Binding Protein Has Secondary Thermal 9- cis -Retinal Isomerase ActivityMolecular Basis for Vitamin A Uptake and Storage in VertebratesRetinol Dehydrogenases Regulate Vitamin A Metabolism for Visual FunctionMüller glial cell-dependent regeneration of the neural retina: An overview across vertebrate model systemsAn Endogenous Mammalian Retinoid X Receptor Ligand, At Last!Chemistry of the retinoid (visual) cycleRDH13L, an enzyme responsible for the aldehyde-alcohol redox coupling reaction (AL-OL coupling reaction) to supply 11-cis retinal in the carp cone retinoid cycleIdentification of the 11-cis-specific retinyl-ester synthase in retinal Müller cells as multifunctional O-acyltransferase (MFAT).Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate.Chromophore supply rate-limits mammalian photoreceptor dark adaptation.Retinal degeneration in animal models with a defective visual cycle.Interphotoreceptor retinoid-binding protein (IRBP) promotes retinol uptake and release by rat Müller cells (rMC-1) in vitro: implications for the cone visual cycleSelective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.Similar molecules spatially correlate with lipofuscin and N-retinylidene-N-retinylethanolamine in the mouse but not in the human retinal pigment epithelium.CRALBP supports the mammalian retinal visual cycle and cone vision.Diacylglycerol O-acyltransferase type-1 synthesizes retinyl esters in the retina and retinal pigment epitheliumΔ10(E)-Sphingolipid Desaturase Involved in Fusaruside Mycosynthesis and Stress Adaptation in Fusarium graminearumImprovement in vision: a new goal for treatment of hereditary retinal degenerationsLong-term effect of gene therapy on Leber's congenital amaurosis.Retinal Gene Therapy: Current Progress and Future Prospects.Human retinal gene therapy for Leber congenital amaurosis shows advancing retinal degeneration despite enduring visual improvementIntervisit variability of visual parameters in Leber congenital amaurosis caused by RPE65 mutationsComplementation test of Rpe65 knockout and tvrm148.New insights into retinoid metabolism and cycling within the retinaRed-shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina.Retinoids and Retinal Diseases.Immuno-histochemical analysis of rod and cone reaction to RPE65 deficiency in the inferior and superior canine retina.Arap1 Deficiency Causes Photoreceptor Degeneration in Mice.The use of cultured human fetal retinal pigment epithelium in studies of the classical retinoid visual cycle and retinoid-based disease processes.Photo-damage, photo-protection and age-related macular degeneration.Melanopsin and the Non-visual Photochemistry in the Inner Retina of Vertebrates.Retinol dehydrogenase 8 and ATP-binding cassette transporter 4 modulate dark adaptation of M-cones in mammalian retina.Allosteric modulation of the substrate specificity of acyl-CoA wax alcohol acyltransferase 2.The role of retinol dehydrogenase 10 in the cone visual cycle.Substrate specificity and subcellular localization of the aldehyde-alcohol redox-coupling reaction in carp cones.Peropsin modulates transit of vitamin A from retina to retinal pigment epithelium.RPE65 has an additional function as the lutein to meso-zeaxanthin isomerase in the vertebrate eye.The retina visual cycle is driven by cis retinol oxidation in the outer segments of cones.
P2860
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P2860
Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
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2012年學術文章
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name
Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina.
@ast
Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina.
@en
type
label
Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina.
@ast
Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina.
@en
prefLabel
Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina.
@ast
Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina.
@en
P2093
P2860
P921
P356
P1476
Identification of DES1 as a vitamin A isomerase in Müller glial cells of the retina.
@en
P2093
C Nathaniel Roybal
Gabriel H Travis
Jacob Makshanoff
Jeremy Cook
Joanna J Kaylor
Samer Habib
P2860
P2888
P356
10.1038/NCHEMBIO.1114
P577
2012-11-11T00:00:00Z