Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis
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Mitochondria and ageing: role in heart, skeletal muscle and adipose tissue.CLD1 Reverses the Ubiquinone Insufficiency of Mutant cat5/coq7 in a Saccharomyces cerevisiae Model System.Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects.Impact of Chemical Analogs of 4-Hydroxybenzoic Acid on Coenzyme Q Biosynthesis: From Inhibition to Bypass of Coenzyme Q Deficiency.Rescue of primary ubiquinone deficiency due to a novel COQ7 defect using 2,4-dihydroxybensoic acid.Pathogenicity of two COQ7 mutations and responses to 2,4-dihydroxybenzoate bypass treatmentA single biochemical activity underlies the pleiotropy of the aging-related protein CLK-1.The role of mitochondrial ROS in the aging brain.Estimating the occurrence of primary ubiquinone deficiency by analysis of large-scale sequencing data.Biochemistry of Mitochondrial Coenzyme Q Biosynthesis.RNA-binding proteins regulate cell respiration and coenzyme Q biosynthesis by post-transcriptional regulation of COQ7.Kaempferol increases levels of coenzyme Q in kidney cells and serves as a biosynthetic ring precursor.Lifelong reduction in complex IV induces tissue-specific metabolic effects but does not reduce lifespan or healthspan in mice.Low-level mitochondrial heteroplasmy modulates DNA replication, glucose metabolism and lifespan in mice.Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis
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P2860
Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年学术文章
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2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis
@ast
Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis
@en
type
label
Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis
@ast
Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis
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prefLabel
Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis
@ast
Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis
@en
P2093
P2860
P356
P1476
Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis
@en
P2093
Daniella Oxer
Siegfried Hekimi
P2860
P2888
P356
10.1038/NCOMMS7393
P407
P577
2015-03-06T00:00:00Z