Phosphorothioate oligodeoxynucleotides--anti-sense inhibitors of gene expression?
about
Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimersIn vitro inhibition of hepatitis C virus gene expression by chemically modified antisense oligodeoxynucleotidesAntisense oligodeoxynucleotide phosphorothioate complementary to Gag mRNA blocks replication of human immunodeficiency virus type 1 in human peripheral blood cellsLong-term treatment of human immunodeficiency virus-infected cells with antisense oligonucleotide phosphorothioatesStructure/affinity studies in the bicyclo-DNA series: Synthesis and properties of oligonucleotides containing bc(en)-T and iso-tricyclo-T nucleosides.The anti-inflammatory activity of a novel fused-cyclopentenone phosphonate and its potential in the local treatment of experimental colitis.Antisense phosphorothioate oligodeoxynucleotides targeted to the vpr gene inhibit human immunodeficiency virus type 1 replication in primary human macrophagesBinding of phosphorothioate oligodeoxynucleotides to basic fibroblast growth factor, recombinant soluble CD4, laminin and fibronectin is P-chirality independent.Phosphorothioate oligonucleotides bind in a non sequence-specific manner to the nucleolar protein C23/nucleolin.2'-O,4'-C-aminomethylene-bridged nucleic acid modification with enhancement of nuclease resistance promotes pyrimidine motif triplex nucleic acid formation at physiological pH.Interrupted 2'-o,4'-C-aminomethylene bridged nucleic acid modification enhances pyrimidine motif triplex-forming ability and nuclease resistance under physiological condition.Enhanced activity of an antisense oligonucleotide targeting murine protein kinase C-alpha by the incorporation of 2'-O-propyl modificationsOligodeoxynucleoside phosphoramidates (P-NH2): synthesis and thermal stability of duplexes with DNA and RNA targetsEfficient in vitro inhibition of HIV-1 gag reverse transcription by peptide nucleic acid (PNA) at minimal ratios of PNA/RNA.Antisense oligonucleotides in the study of neuroendocrine systems.Analysis of oligo(deoxynucleoside phosphorothioate)s and their diastereomeric composition.An assessment of the antisense properties of RNase H-competent and steric-blocking oligomers.New efficient sulfurizing reagents for the preparation of oligodeoxyribonucleotide phosphorothioate analoguesDevelopment of antisense therapeutics. Implications for cancer gene therapy.Uptake and intracellular distribution of oligonucleotides vectorized by a PAMAM dendrimer.Emerging therapies for hepatitis C virus infection.Gas-phase dissociation of oligoribonucleotides and their analogs studied by electrospray ionization tandem mass spectrometry.Antisense inhibition of chondrocyte CD44 expression leading to cartilage chondrolysis.
P2860
Q24547040-D28EFFB4-A836-4A64-96B7-9FBC3EA75B8AQ27477597-2521CEE6-EBB8-4D15-8516-E18948391253Q28369354-CC37B12B-F173-4BD1-809E-244F13BBA075Q28378692-C388D2F7-D751-4581-B4B1-4E5B1391DF29Q34082208-351586F7-E843-47ED-95DD-5093A7D781E7Q35534551-8B6C4E36-705F-407D-8CA0-3B12821CDFE5Q36650619-32192CB1-FADD-4E3E-91DD-5C4C7EAE023EQ38289315-48C3D624-02AA-4CA4-8365-2BE83AA5A02AQ38294320-B0A840AE-0B9F-4001-8363-18CA691CC50CQ38337867-6E0BBC06-A690-4708-ADEC-701F5516A8C8Q38337896-A6C1AF2F-3A7F-41D1-BAC1-FDE25BAA311DQ39715452-85BD2883-4C0E-4EF4-BB32-3B7D27C6D256Q39716323-7258824E-4489-4235-9648-4A2378E17EADQ39720212-37941798-6D45-43A2-B045-FD0D326C8BA1Q40381168-6CD92D69-6306-420D-8B24-331F906D4398Q40392939-46AFEE65-A446-475C-9DDB-937A4613E462Q40393595-E90904D6-3ACA-4CD3-9569-5937FCDD62F0Q40396267-6F7A3B19-D7FE-4423-A4A9-B940AA34655FQ40667901-65999831-42D3-4AFD-91FD-BFA4BB7266B9Q42811220-1B669446-FC4E-4B16-BAB9-F41506B89EB4Q45440609-576F3627-272D-43E5-A1B4-0CB5F78A80DAQ46566925-7ED844E5-CC24-450F-A342-69043E783DDBQ47685814-9174A11A-0E88-4DA0-8FC7-93DAD75EF5E2
P2860
Phosphorothioate oligodeoxynucleotides--anti-sense inhibitors of gene expression?
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年学术文章
@wuu
1991年学术文章
@zh-cn
1991年学术文章
@zh-hans
1991年学术文章
@zh-my
1991年学术文章
@zh-sg
1991年學術文章
@yue
1991年學術文章
@zh
1991年學術文章
@zh-hant
name
Phosphorothioate oligodeoxynucleotides--anti-sense inhibitors of gene expression?
@ast
Phosphorothioate oligodeoxynucleotides--anti-sense inhibitors of gene expression?
@en
type
label
Phosphorothioate oligodeoxynucleotides--anti-sense inhibitors of gene expression?
@ast
Phosphorothioate oligodeoxynucleotides--anti-sense inhibitors of gene expression?
@en
prefLabel
Phosphorothioate oligodeoxynucleotides--anti-sense inhibitors of gene expression?
@ast
Phosphorothioate oligodeoxynucleotides--anti-sense inhibitors of gene expression?
@en
P2093
P1476
Phosphorothioate oligodeoxynucleotides--anti-sense inhibitors of gene expression?
@en
P2093
P304
P356
10.1016/0163-7258(91)90032-H
P577
1991-12-01T00:00:00Z