RECQ1 is required for cellular resistance to replication stress and catalyzes strand exchange on stalled replication fork structures.
about
The role of RecQ helicases in non-homologous end-joiningHuman RECQL1 participates in telomere maintenanceIdentification of RECQ1-regulated transcriptome uncovers a role of RECQ1 in regulation of cancer cell migration and invasion.The intrinsically disordered amino-terminal region of human RecQL4: multiple DNA-binding domains confer annealing, strand exchange and G4 DNA binding.RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin.DNA helicases involved in DNA repair and their roles in cancerHuman RecQ helicases in DNA repair, recombination, and replication.A new sub-pathway of long-patch base excision repair involving 5' gap formation.RECQ helicases are deregulated in hematological malignancies in association with a prognostic valueReplication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16DAltered RECQ Helicase Expression in Sporadic Primary Colorectal Cancers.Targeting homologous recombination-mediated DNA repair in cancer.Probing Genome Maintenance Functions of human RECQ1.Clinicopathological and Functional Significance of RECQL1 Helicase in Sporadic Breast Cancers.RECQ1 helicase is involved in replication stress survival and drug resistance in multiple myelomaZNF365 promotes stalled replication forks recovery to maintain genome stability.Transcriptome guided identification of novel functions of RECQ1 helicase.An appraisal of RECQ1 expression in cancer progression.RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner.Low expression of RECQL is associated with poor prognosis in Chinese breast cancer patients.
P2860
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P2860
RECQ1 is required for cellular resistance to replication stress and catalyzes strand exchange on stalled replication fork structures.
description
2012 nî lūn-bûn
@nan
2012年の論文
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2012年学术文章
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2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
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name
RECQ1 is required for cellular ...... d replication fork structures.
@ast
RECQ1 is required for cellular ...... d replication fork structures.
@en
type
label
RECQ1 is required for cellular ...... d replication fork structures.
@ast
RECQ1 is required for cellular ...... d replication fork structures.
@en
prefLabel
RECQ1 is required for cellular ...... d replication fork structures.
@ast
RECQ1 is required for cellular ...... d replication fork structures.
@en
P2093
P2860
P356
P1433
P1476
RECQ1 is required for cellular ...... d replication fork structures.
@en
P2093
Deborah L Croteau
Robert M Brosh
Venkateswarlu Popuri
Vilhelm A Bohr
P2860
P304
P356
10.4161/CC.22581
P577
2012-10-24T00:00:00Z