Furin-cleaved proprotein convertase subtilisin/kexin type 9 (PCSK9) is active and modulates low density lipoprotein receptor and serum cholesterol levels.
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New developments in atherosclerosis: clinical potential of PCSK9 inhibitionThe multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functionsE2F1 inhibits circulating cholesterol clearance by regulating Pcsk9 expression in the liver.Molecular and cellular function of the proprotein convertase subtilisin/kexin type 9 (PCSK9).Biology of proprotein convertase subtilisin kexin 9: beyond low-density lipoprotein cholesterol lowering.PCSK9 inhibition to reduce cardiovascular disease risk: recent findings from the biology of PCSK9.High-fructose feeding promotes accelerated degradation of hepatic LDL receptor and hypercholesterolemia in hamsters via elevated circulating PCSK9 levelsOn the function and homeostasis of PCSK9: reciprocal interaction with LDLR and additional lipid effects.Loss of plasma proprotein convertase subtilisin/kexin 9 (PCSK9) after lipoprotein apheresis.Proprotein convertases subtilisin/kexin type 9, an enzyme turned escort protein: hepatic and extra hepatic functions.The biology of PCSK9 from the endoplasmic reticulum to lysosomes: new and emerging therapeutics to control low-density lipoprotein cholesterol.Alirocumab: PCSK9 inhibitor for LDL cholesterol reduction.PCSK9 in chronic kidney disease.Studies of the autoinhibitory segment comprising residues 31-60 of the prodomain of PCSK9: Possible implications for the mechanism underlying gain-of-function mutations.Expression levels and clinical significance of hepsin and HMGB1 proteins in cervical carcinomaThe Central Role of Proprotein Convertase Subtilisin/Kexin Type 9 in Septic Pathogen Lipid Transport and Clearance.Isolation and characterization of the circulating truncated form of PCSK9Proteolytic cleavage of antigen extends the durability of an anti-PCSK9 monoclonal antibody.Threshold Effects of Circulating Angiopoietin-Like 3 Levels on Plasma Lipoproteins.Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists.Cinnamomum osmophloeum Kanehira ethanol extracts prevents human liver-derived HepG2 cell death from oxidation stress by induction of ghrelin gene expression.
P2860
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P2860
Furin-cleaved proprotein convertase subtilisin/kexin type 9 (PCSK9) is active and modulates low density lipoprotein receptor and serum cholesterol levels.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
2012年學術文章
@zh
2012年學術文章
@zh-hant
name
Furin-cleaved proprotein conve ...... and serum cholesterol levels.
@ast
Furin-cleaved proprotein conve ...... and serum cholesterol levels.
@en
type
label
Furin-cleaved proprotein conve ...... and serum cholesterol levels.
@ast
Furin-cleaved proprotein conve ...... and serum cholesterol levels.
@en
prefLabel
Furin-cleaved proprotein conve ...... and serum cholesterol levels.
@ast
Furin-cleaved proprotein conve ...... and serum cholesterol levels.
@en
P2093
P2860
P356
P1476
Furin-cleaved proprotein conve ...... and serum cholesterol levels.
@en
P2093
Andrew S Peterson
Anita Izrael-Tomasevic
Daniel Kirchhofer
David Arnott
Ganesh Kolumam
Jianyong Wang
Jose Zavala-Solorio
Michael T Lipari
Monica Kong-Beltran
P2860
P304
43482-43491
P356
10.1074/JBC.M112.380618
P407
P577
2012-11-07T00:00:00Z