Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear fact

Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear fact

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http://www.wikidata.org/entity/Q36481790

Q36481790

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Proteoglycan form and function: A comprehensive nomenclature of proteoglycans Decorin causes autophagy in endothelial cells via Peg3 Endorepellin laminin-like globular 1/2 domains bind Ig3-5 of vascular endothelial growth factor (VEGF) receptor 2 and block pro-angiogenic signaling by VEGFA in endothelial cells Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells Chronic over-nutrition and dysregulation of GSK3 in diseases Oncosuppressive functions of decorin Matricryptins Network with Matricellular Receptors at the Surface of Endothelial and Tumor Cells The role of perlecan and endorepellin in the control of tumor angiogenesis and endothelial cell autophagy Decoding the Matrix: Instructive Roles of Proteoglycan Receptors Molecular testing in lung cancer in the era of precision medicine Extracellular Matrix, a Hard Player in Angiogenesis Insights into the key roles of proteoglycans in breast cancer biology and translational medicine A current view of perlecan in physiology and pathology: A mosaic of functions.Endorepellin evokes autophagy in endothelial cells Extracellular matrix modulates angiogenesis in physiological and pathological conditions.Blood vessel repair and regeneration in the ischaemic heart Endostatin and endorepellin: A common route of action for similar angiostatic cancer avengers Decorin induces rapid secretion of thrombospondin-1 in basal breast carcinoma cells via inhibition of Ras homolog gene family, member A/Rho-associated coiled-coil containing protein kinase 1.Proteoglycans regulate autophagy via outside-in signaling: an emerging new concept.Reprint of: Decorin activates AMPK, an energy sensor kinase, to induce autophagy in endothelial cells.Decorin-inducible Peg3 Evokes Beclin 1-mediated Autophagy and Thrombospondin 1-mediated Angiostasis Perlecan domain V therapy for stroke: a beacon of hope?Instructive roles of extracellular matrix on autophagy.Proteoglycans: Potential Agents in Mammographic Density and the Associated Breast Cancer Risk.Molecular Functions of Glycoconjugates in Autophagy.Endorepellin-evoked Autophagy Contributes to Angiostasis.VEGF-A isoform-specific regulation of calcium ion flux, transcriptional activation and endothelial cell migration.Decorin-evoked paternally expressed gene 3 (PEG3) is an upstream regulator of the transcription factor EB (TFEB) in endothelial cell autophagy.Extracellular matrix: The driving force of mammalian diseases.

P2860

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Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear fact

Item

http://www.wikidata.org/entity/Q36481790

description

2012 nî lūn-bûn

@nan

2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

@zh-hans

2012年学术文章

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2012年学术文章

@zh-sg

2012年學術文章

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2012年學術文章

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2012年學術文章

@zh-hant

name

Endorepellin affects angiogene ...... ent inhibition of nuclear fact

@ast

Endorepellin affects angiogene ...... ent inhibition of nuclear fact

@en

type

Item

label

Endorepellin affects angiogene ...... ent inhibition of nuclear fact

@ast

Endorepellin affects angiogene ...... ent inhibition of nuclear fact

@en

prefLabel

Endorepellin affects angiogene ...... ent inhibition of nuclear fact

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Endorepellin affects angiogene ...... ent inhibition of nuclear fact

@en

P1476

Endorepellin affects angiogene ...... ent inhibition of nuclear fact

@en

P2093

Atul Goyal

http://www.w3.org/2001/XMLSchema#string

Chiara Poluzzi

http://www.w3.org/2001/XMLSchema#string

Chris D Willis

http://www.w3.org/2001/XMLSchema#string

James Smythies

http://www.w3.org/2001/XMLSchema#string

Thomas Neill

http://www.w3.org/2001/XMLSchema#string

P2860

Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

Endorepellin, the angiostatic module of perlecan, interacts with both the α2β1 integrin and vascular endothelial growth factor receptor 2 (VEGFR2): a dual receptor antagonism

Effective suppression of vascular network formation by combination of antibodies blocking VEGFR ligand binding and receptor dimerization

Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor

Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo

Suppression of autocrine and paracrine functions of basic fibroblast growth factor by stable expression of perlecan antisense cDNA

Parallel phosphatidylinositol 3-kinase (PI3K)-dependent and Src-dependent pathways lead to CXCL8-mediated Rac2 activation and chemotaxis

A central function for perlecan in skeletal muscle and cardiovascular development

Perlecan regulates developmental angiogenesis by modulating the VEGF-VEGFR2 axis.

P304

43543-43556

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P31

scholarly article

P356

10.1074/JBC.M112.401786

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English

P433

http://www.w3.org/2001/XMLSchema#string

P478

287

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P50

Renato V. Iozzo

Adam Shellard

P577

2012-10-11T00:00:00Z

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P5875

232236625

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P698

23060442

http://www.w3.org/2001/XMLSchema#string

P921

hypoxia

endothelium

P932

3527941

http://www.w3.org/2001/XMLSchema#string

Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear fact

about

P2860

P2860

Endorepellin affects angiogenesis by antagonizing diverse vascular endothelial growth factor receptor 2 (VEGFR2)-evoked signaling pathways: transcriptional repression of hypoxia-inducible factor 1α and VEGFA and concurrent inhibition of nuclear fact

description

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type

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P1433

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P2860

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P921

P932

P356

P1433

P1476

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P356

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P932