Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration.
about
Regulated expression of the Ras effector Rin1 in forebrain neuronsABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1.Enhancement of ABL kinase catalytic efficiency by a direct binding regulator is independent of other regulatory mechanisms.RIN3 is a negative regulator of mast cell responses to SCF.Fear learning and extinction are linked to neuronal plasticity through Rin1 signaling.Rab5-mediated endocytosis of activin is not required for gene activation or long-range signalling in XenopusATM is down-regulated by N-Myc-regulated microRNA-421.Compartmentalized Ras proteins transform NIH 3T3 cells with different efficienciesThe RAB5-GEF function of RIN1 regulates multiple steps during Listeria monocytogenes infectionMiR-373 targeting of the Rab22a oncogene suppresses tumor invasion and metastasis in ovarian cancer.Tyrosine phosphorylation of RAS by ABL allosterically enhances effector bindingFeedback regulation of Ras signaling by Rabex-5-mediated ubiquitinationElevated RABEX-5 expression predicts poor prognosis in non-small-cell lung cancer.RIN1 orchestrates the activation of RAB5 GTPases and ABL tyrosine kinases to determine the fate of EGFR.LncRNA HOTAIR controls the expression of Rab22a by sponging miR-373 in ovarian cancer.Hypoxia promotes Rab5 activation, leading to tumor cell migration, invasion and metastasis.Ras and Rab interactor 1 controls neuronal plasticity by coordinating dendritic filopodial motility and AMPA receptor turnover.The crosstalk of RAS with the TGF-β family during carcinoma progression and its implications for targeted cancer therapy.Post-translational regulation of TGF-β receptor and Smad signaling.Cell proliferation and epidermal growth factor signaling in non-small cell lung adenocarcinoma cell lines are dependent on Rin1.Elevated RABEX-5 protein expression predicts poor prognosis in combined small cell lung cancer.RIN1 promotes renal cell carcinoma malignancy by activating EGFR signaling through Rab25RIN1 regulates cell migration through RAB5 GTPases and ABL tyrosine kinases.Zoledronic acid suppresses transforming growth factor-β-induced fibrogenesis by human gingival fibroblasts.A novel protein kinase D phosphorylation site in the tumor suppressor Rab interactor 1 is critical for coordination of cell migrationIntracellular trafficking of transforming growth factor β receptors.Potential microRNA-related Targets for Therapeutic Intervention with Ovarian Cancer Metastasis.
P2860
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P2860
Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor-directed cell migration.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Integration of transforming gr ...... actor-directed cell migration.
@ast
Integration of transforming gr ...... actor-directed cell migration.
@en
type
label
Integration of transforming gr ...... actor-directed cell migration.
@ast
Integration of transforming gr ...... actor-directed cell migration.
@en
prefLabel
Integration of transforming gr ...... actor-directed cell migration.
@ast
Integration of transforming gr ...... actor-directed cell migration.
@en
P2093
P2860
P356
P1476
Integration of transforming gr ...... actor-directed cell migration.
@en
P2093
Gautam Malhotra
Hailiang Hu
Joanne M Bliss
John Colicelli
Lucia C Huynh
Marc Milstein
P2860
P304
P356
10.1128/MCB.01087-07
P407
P577
2007-12-26T00:00:00Z