Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes.
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Streptococcal toxic-shock syndrome: spectrum of disease, pathogenesis, and new concepts in treatmentViable group A streptococci in macrophages during acute soft tissue infectionGenome-wide analysis of group a streptococci reveals a mutation that modulates global phenotype and disease specificity.Inflammasome/IL-1β Responses to Streptococcal PathogensCrystal structure of the zymogen form of the group A Streptococcus virulence factor SpeB: An integrin-binding cysteine proteaseUltrahigh and High Resolution Structures and Mutational Analysis of Monomeric Streptococcus pyogenes SpeB Reveal a Functional Role for the Glycine-rich C-terminal LoopLocalization and functionality of the inflammasome in neutrophilsDispersal of Group A streptococcal biofilms by the cysteine protease SpeB leads to increased disease severity in a murine modelPathogenesis of group A streptococcal infectionsIdeS, a novel streptococcal cysteine proteinase with unique specificity for immunoglobulin G.Uptake and intracellular transportation of a bacterial surface protein in lymphoid cells.alpha2-Macroglobulin-proteinase complexes protect Streptococcus pyogenes from killing by the antimicrobial peptide LL-37.EndoS from Streptococcus pyogenes is hydrolyzed by the cysteine proteinase SpeB and requires glutamic acid 235 and tryptophans for IgG glycan-hydrolyzing activitySpeB of Streptococcus pyogenes differentially modulates antibacterial and receptor activating properties of human chemokines.Absence of a cysteine protease effect on bacterial virulence in two murine models of human invasive group A streptococcal infection.Interleukin 18 restores defective Th1 immunity to Candida albicans in caspase 1-deficient miceAllelic replacement of the streptococcal cysteine protease SpeB in a Δsrv mutant background restores biofilm formation.Genetic inactivation of an extracellular cysteine protease (SpeB) expressed by Streptococcus pyogenes decreases resistance to phagocytosis and dissemination to organsEffect of group A streptococcal cysteine protease on invasion of epithelial cells.Opsonic antibodies to the surface M protein of group A streptococci in pooled normal immunoglobulins (IVIG): potential impact on the clinical efficacy of IVIG therapy for severe invasive group A streptococcal infections.Role of streptococcal pyrogenic exotoxin B in the mouse model of group A streptococcal infection.The M protein is dispensable for maturation of streptococcal cysteine protease SpeB.A role for trigger factor and an rgg-like regulator in the transcription, secretion and processing of the cysteine proteinase of Streptococcus pyogenes.Inhibition of Inflammasome-Dependent Interleukin 1β Production by Streptococcal NAD+-Glycohydrolase: Evidence for Extracellular Activity.Invasive and noninvasive group A streptococcal isolates with different speA alleles in The Netherlands: genetic relatedness and production of pyrogenic exotoxins A and BStreptococcal pyrogenic exotoxin B induces apoptosis and reduces phagocytic activity in U937 cells.An extracellular protease of Streptococcus gordonii hydrolyzes type IV collagen and collagen analogues.The rgg gene of Streptococcus pyogenes NZ131 positively influences extracellular SPE B production.Fibrinogen cleavage by the Streptococcus pyogenes extracellular cysteine protease and generation of antibodies that inhibit enzyme proteolytic activity.Group A Streptococcus induces apoptosis in human epithelial cells.Absence of SpeB production in virulent large capsular forms of group A streptococcal strain 64Streptococcal erythrogenic toxin B abrogates fibronectin-dependent internalization of Streptococcus pyogenes by cultured mammalian cellsReplacement of histidine 340 with alanine inactivates the group A Streptococcus extracellular cysteine protease virulence factorInverse relation between disease severity and expression of the streptococcal cysteine protease, SpeB, among clonal M1T1 isolates recovered from invasive group A streptococcal infection casesGroup A streptococcus--from basic science to clinical disease.From transcription to activation: how group A streptococcus, the flesh-eating pathogen, regulates SpeB cysteine protease production.Cysteine proteinase SpeB from Streptococcus pyogenes - a potent modifier of immunologically important host and bacterial proteins.The contribution of group A streptococcal virulence determinants to the pathogenesis of sepsis.A natural variant of the cysteine protease virulence factor of group A Streptococcus with an arginine-glycine-aspartic acid (RGD) motif preferentially binds human integrins alphavbeta3 and alphaIIbbeta3.Superantigenic properties of the group A streptococcal exotoxin SpeF (MF).
P2860
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P2860
Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes.
description
1993 nî lūn-bûn
@nan
1993年の論文
@ja
1993年学术文章
@wuu
1993年学术文章
@zh-cn
1993年学术文章
@zh-hans
1993年学术文章
@zh-my
1993年学术文章
@zh-sg
1993年學術文章
@yue
1993年學術文章
@zh
1993年學術文章
@zh-hant
name
Cleavage of interleukin 1 beta ...... e from Streptococcus pyogenes.
@ast
Cleavage of interleukin 1 beta ...... e from Streptococcus pyogenes.
@en
type
label
Cleavage of interleukin 1 beta ...... e from Streptococcus pyogenes.
@ast
Cleavage of interleukin 1 beta ...... e from Streptococcus pyogenes.
@en
prefLabel
Cleavage of interleukin 1 beta ...... e from Streptococcus pyogenes.
@ast
Cleavage of interleukin 1 beta ...... e from Streptococcus pyogenes.
@en
P2093
P2860
P356
P1476
Cleavage of interleukin 1 beta ...... e from Streptococcus pyogenes.
@en
P2093
P2860
P304
P356
10.1073/PNAS.90.16.7676
P407
P577
1993-08-01T00:00:00Z