Remarkable Phenytoin Sensitivity in 4 Children with SCN8A-related Epilepsy: A Molecular Neuropharmacological Approach
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The SCN8A encephalopathy mutation p.Ile1327Val displays elevated sensitivity to the anticonvulsant phenytoin.SCN8A encephalopathy: Research progress and prospectsGene Panel Testing in Epileptic Encephalopathies and Familial Epilepsies.Comparative effectiveness of antiepileptic drugs in patients with mesial temporal lobe epilepsy with hippocampal sclerosis.Precision medicine in genetic epilepsies: break of dawn?Recent advances in epilepsy.Pharmacogenomics in epilepsy.The Impact of Next-Generation Sequencing on the Diagnosis and Treatment of Epilepsy in Paediatric Patients.Stiripentol in the Management of Epilepsy.Models for discovery of targeted therapy in genetic epileptic encephalopathies.Dravet syndrome and its mimics: Beyond SCN1A.SCN8A mutations in Chinese patients with early onset epileptic encephalopathy and benign infantile seizuresAberrant epilepsy-associated mutant Nav1.6 sodium channel activity can be targeted with cannabidiol.Phenytoin-responsive epileptic encephalopathy with a tandem duplication involving FGF12Rapid and safe response to low-dose carbamazepine in neonatal epilepsy.Ion Channels in Genetic Epilepsy: From Genes and Mechanisms to Disease-Targeted Therapies.De novo variants in the alternative exon 5 of SCN8A cause epileptic encephalopathy.Phenytoin: a step by step insight into its multiple mechanisms of action-80 years of mechanistic studies in neuropharmacology.Recent Advances in Neonatal Seizures.A Model Program for Translational Medicine in Epilepsy Genetics.Phenytoin as a last-resort treatment in SCN8A encephalopathy.Mutations in SCN3A cause early infantile epileptic encephalopathyThe novel sodium channel modulator GS-458967 (GS967) is an effective treatment in a mouse model of SCN8A encephalopathy
P2860
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P2860
Remarkable Phenytoin Sensitivity in 4 Children with SCN8A-related Epilepsy: A Molecular Neuropharmacological Approach
description
2015 nî lūn-bûn
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2015年の論文
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2015年学术文章
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2015年学术文章
@zh-cn
2015年学术文章
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2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
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2015年學術文章
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2015年學術文章
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name
Remarkable Phenytoin Sensitivi ...... Neuropharmacological Approach
@ast
Remarkable Phenytoin Sensitivi ...... Neuropharmacological Approach
@en
type
label
Remarkable Phenytoin Sensitivi ...... Neuropharmacological Approach
@ast
Remarkable Phenytoin Sensitivi ...... Neuropharmacological Approach
@en
prefLabel
Remarkable Phenytoin Sensitivi ...... Neuropharmacological Approach
@ast
Remarkable Phenytoin Sensitivi ...... Neuropharmacological Approach
@en
P2093
P2860
P50
P1433
P1476
Remarkable Phenytoin Sensitivi ...... Neuropharmacological Approach
@en
P2093
Bobby P C Koeleman
Eva H Brilstra
Eveline O Hagebeuk
Frederique M C van Berkestijn
Joost Nicolai
Kees P Braun
Maartje Boon
Marcel P H van den Broek
Marielle E Swinkels
Marjan van Kempen
P2860
P2888
P304
P356
10.1007/S13311-015-0372-8
P577
2015-08-09T00:00:00Z