BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones. - Wikidata - awgldk - TriplyDB

BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones.

BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones.

http://www.wikidata.org/entity/Q36485411

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Post-transcriptional gene silencing, transcriptional gene silencing and human immunodeficiency virus The Bromodomain and Extra-Terminal Domain (BET) Family: Functional Anatomy of BET Paralogous Proteins RNA Polymerase II Regulates Topoisomerase 1 Activity to Favor Efficient Transcription.Clinical Response of Carcinomas Harboring the BRD4-NUT Oncoprotein to the Targeted Bromodomain Inhibitor OTX015/MK-8628 BRD4 promotes p63 and GRHL3 expression downstream of FOXO in mammary epithelial cells Higher-Order Chromatin Regulation of Inflammatory Gene Expression Bromodomain factors of BET family are new essential actors of pericentric heterochromatin transcriptional activation in response to heat shock Enhancers as non-coding RNA transcription units: recent insights and future perspectives.The molecular mechanics of mixed lineage leukemia.PAPST, a User Friendly and Powerful Java Platform for ChIP-Seq Peak Co-Localization Analysis and Beyond.H4K12ac is regulated by estrogen receptor-alpha and is associated with BRD4 function and inducible transcription.Sex comb on midleg (Scm) is a functional link between PcG-repressive complexes in Drosophila The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation.High-throughput single-molecule screen for small-molecule perturbation of splicing and transcription kinetics.The oncogenic BRD4-NUT chromatin regulator drives aberrant transcription within large topological domains.GC skew defines distinct RNA polymerase pause sites in CpG island promoters.Transcriptional and post-transcriptional control of adipocyte differentiation by Jumonji domain-containing protein 6.CCAT1 is an enhancer-templated RNA that predicts BET sensitivity in colorectal cancer BET Bromodomain Blockade Mitigates Intimal Hyperplasia in Rat Carotid Arteries.BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice Targeting the EWS-ETS transcriptional program by BET bromodomain inhibition in Ewing sarcoma.BET Inhibition Attenuates Helicobacter pylori-Induced Inflammatory Response by Suppressing Inflammatory Gene Transcription and Enhancer Activation.Kinase and BET Inhibitors Together Clamp Inhibition of PI3K Signaling and Overcome Resistance to Therapy.Histone Deacetylases Positively Regulate Transcription through the Elongation Machinery.Chromatin architecture underpinning transcription elongation Erythropoiesis provides a BRD's eye view of BET protein function.Enhancer-associated RNAs as therapeutic targets.AIRE: From promiscuous molecular partnerships to promiscuous gene expression.The Short Isoform of BRD4 Promotes HIV-1 Latency by Engaging Repressive SWI/SNF Chromatin-Remodeling Complexes.Targeting epigenetic regulators for cancer therapy: modulation of bromodomain proteins, methyltransferases, demethylases, and microRNAs.BRD4 Couples NF-κB/RelA with Airway Inflammation and the IRF-RIG-I Amplification Loop in Respiratory Syncytial Virus Infection.Epigenetic regulation of cardiac fibrosis.BRD4 localization to lineage-specific enhancers is associated with a distinct transcription factor repertoire.Compensatory RNA polymerase 2 loading determines the efficacy and transcriptional selectivity of JQ1 in Myc-driven tumors.Autoimmune regulator and self-tolerance - molecular and clinical aspects.Bromodomain 4: a cellular Swiss army knife Regulation of RNA polymerase II-mediated transcriptional elongation: Implications in human disease.New insights into the immunopathogenesis of systemic lupus erythematosus.A Novel Epi-drug Therapy Based on the Suppression of BET Family Epigenetic Readers.Enhancer-derived RNA: A Primer

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P2860

BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones.

http://www.wikidata.org/entity/Q36485411

description

2014 nî lūn-bûn

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2014年の論文

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年学术文章

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2014年學術文章

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2014年學術文章

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2014年學術文章

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BRD4 assists elongation of bot ...... ting with acetylated histones.

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BRD4 assists elongation of bot ...... ting with acetylated histones.

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BRD4 assists elongation of bot ...... ting with acetylated histones.

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Nature Structural & Molecular Biology

P1476

BRD4 assists elongation of bot ...... ting with acetylated histones.

@en

P2093

Benjamin A Garcia

http://www.w3.org/2001/XMLSchema#string

Eric Campos

http://www.w3.org/2001/XMLSchema#string

Gary LeRoy

http://www.w3.org/2001/XMLSchema#string

Golnaz Vahedi

http://www.w3.org/2001/XMLSchema#string

Hong-Wei Sun

http://www.w3.org/2001/XMLSchema#string

John J O'Shea

http://www.w3.org/2001/XMLSchema#string

Keiko Ozato

http://www.w3.org/2001/XMLSchema#string

Stephen R Brooks

http://www.w3.org/2001/XMLSchema#string

Tom D Heightman

http://www.w3.org/2001/XMLSchema#string

Tomohiko Kanno

http://www.w3.org/2001/XMLSchema#string

P2860

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

Model-based analysis of ChIP-Seq (MACS)

Requirement of RSF and FACT for transcription of chromatin templates in vitro

A bromodomain protein, MCAP, associates with mitotic chromosomes and affects G(2)-to-M transition

The bromodomain protein Brd4 insulates chromatin from DNA damage signalling

Selective inhibition of BET bromodomains

Bromodomain-containing protein 4 (BRD4) regulates RNA polymerase II serine 2 phosphorylation in human CD4+ T cells

Histone recognition and large-scale structural analysis of the human bromodomain family

Brd4 and JMJD6-associated anti-pause enhancers in regulation of transcriptional pause release

The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription

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1047-1057

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scholarly article

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10.1038/NSMB.2912

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12

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P478

21

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P577

2014-11-10T00:00:00Z

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25383670

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4720983

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