Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas. - Wikidata - awgldk - TriplyDB

Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas.

Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas.

http://www.wikidata.org/entity/Q36486875

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Vitamin A, cancer treatment and prevention: the new role of cellular retinol binding proteins The tumor suppressor prostate apoptosis response-4 (Par-4) is regulated by mutant IDH1 and kills glioma stem cells.5-azacytidine reduces methylation, promotes differentiation and induces tumor regression in a patient-derived IDH1 mutant glioma xenograft.Whole-exome sequencing identifies MDH2 as a new familial paraganglioma gene.Tumor-suppressive miR148a is silenced by CpG island hypermethylation in IDH1-mutant gliomas.Downregulation of TES by hypermethylation in glioblastoma reduces cell apoptosis and predicts poor clinical outcome.HSC-explorer: a curated database for hematopoietic stem cells The future of high-grade glioma: Where we are and where are we going.Recurrent 12q13-15 chromosomal aberrations, high frequency of isocitrate dehydrogenase 1 mutations, and absence of high mobility group AT-hook 2 expression in periosteal chondromas.Methylation associated genes contribute to the favorable prognosis of gliomas with isocitrate dehydrogenase 1 mutation.Isocitrate dehydrogenase 1 mutations prime the all-trans retinoic acid myeloid differentiation pathway in acute myeloid leukemia.IGFBP2 expression predicts IDH-mutant glioma patient survival.Clinical aggressiveness of malignant gliomas is linked to augmented metabolism of amino acids.Circulating biomarker panels for targeted therapy in brain tumors.Retinoic acid signaling and neuronal differentiation.Anaplastic glioma: current treatment and management.Efficient Remyelination Requires DNA Methylation.DNA methylation in adult diffuse gliomas.C-terminally truncated form of αB-crystallin is associated with IDH1 R132H mutation in anaplastic astrocytoma.Prognostic role of IDH mutations in gliomas: a meta-analysis of 55 observational studies.Molecular subtypes of glioma identified by genome-wide methylation profiling.DNA methylation in oligodendroglial cells during developmental myelination and in disease.Codeletion of 1p and 19q determines distinct gene methylation and expression profiles in IDH-mutated oligodendroglial tumors.D-2-Hydroxyglutarate Is Necessary and Sufficient for Isocitrate Dehydrogenase 1 Mutant-Induced MIR148A Promoter Methylation.

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P2860

Identification of retinol binding protein 1 promoter hypermethylation in isocitrate dehydrogenase 1 and 2 mutant gliomas.

http://www.wikidata.org/entity/Q36486875

description

2012 nî lūn-bûn

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2012年の論文

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2012年学术文章

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2012年学术文章

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2012年学术文章

@zh-hans

2012年学术文章

@zh-my

2012年学术文章

@zh-sg

2012年學術文章

@yue

2012年學術文章

@zh

2012年學術文章

@zh-hant

name

Identification of retinol bind ...... genase 1 and 2 mutant gliomas.

@ast

Identification of retinol bind ...... genase 1 and 2 mutant gliomas.

@en

type

label

Identification of retinol bind ...... genase 1 and 2 mutant gliomas.

@ast

Identification of retinol bind ...... genase 1 and 2 mutant gliomas.

@en

prefLabel

Identification of retinol bind ...... genase 1 and 2 mutant gliomas.

@ast

Identification of retinol bind ...... genase 1 and 2 mutant gliomas.

@en

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Journal of the National Cancer Institute

P1476

Identification of retinol bind ...... ogenase 1 and 2 mutant gliomas

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P2093

Albert Lai

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Andrew J Kim

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Arthur P Chou

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Bret Harry

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Desiree E Sanchez

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Harley I Kornblum

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Jack Mottahedeh

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Jeffrey Lin

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Julia M Selfridge

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Matthew C Garrett

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P2860

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Reduced representation bisulfite sequencing for comparative high-resolution DNA methylation analysis

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

Identification of a CpG island methylator phenotype that defines a distinct subgroup of glioma

Genome-scale DNA methylation maps of pluripotent and differentiated cells

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

An integrated genomic analysis of human glioblastoma multiforme

IDH1 and IDH2 mutations in gliomas

Comprehensive genomic characterization defines human glioblastoma genes and core pathways

IDH1 mutations are early events in the development of astrocytomas and oligodendrogliomas

P304

1458-1469

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scholarly article

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10.1093/JNCI/DJS357

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19

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104

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David E Piccioni

Robert M. Prins

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2012-09-03T00:00:00Z

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230791429

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22945948

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3529615

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