Thrombin-cofactor interactions: structural insights into regulatory mechanisms.
about
Trypanosoma brucei modifies the tsetse salivary composition, altering the fly feeding behavior that favors parasite transmissionEnsemble refinement shows conformational flexibility in crystal structures of human complement factor DDissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamerModulation of the Coagulation Cascade Using AptamersThrombin hydrolysis of human osteopontin is dependent on thrombin anion-binding exosites.How Na+ activates thrombin--a review of the functional and structural data.Spatial distribution of factor Xa, thrombin, and fibrin(ogen) on thrombi at venous shearNMR resonance assignments of thrombin reveal the conformational and dynamic effects of ligation.A hereditary bleeding disorder resulting from a premature stop codon in thrombomodulin (p.Cys537Stop)Substantial non-electrostatic forces are needed to induce allosteric disruption of thrombin's active site through exosite 2.Characterization of an autosomal dominant bleeding disorder caused by a thrombomodulin mutation.Effect of Toona microcarpa Harms leaf extract on the coagulation system.Novel therapeutic targets for preserving a healthy endothelium: strategies for reducing the risk of vascular and cardiovascular diseaseExosites in the substrate specificity of blood coagulation reactions.Batroxobin binds fibrin with higher affinity and promotes clot expansion to a greater extent than thrombin.Platelets and the antiphospholipid syndrome.Altered fibrinolysis in autosomal dominant thrombomodulin-associated coagulopathy.Quantitative analysis of protease recognition by inhibitors in plasma using microscale thermophoresis.Antithrombotic Effects of Nur77 and Nor1 Are Mediated Through Upregulating Thrombomodulin Expression in Endothelial Cells.Injectable and biodegradable hydrogels: gelation, biodegradation and biomedical applications.Thrombomodulin and the vascular endothelium: insights into functional, regulatory, and therapeutic aspects.Through-bond effects in the ternary complexes of thrombin sandwiched by two DNA aptamers.Characterization of thrombin derived from human recombinant prothrombin.Thrombomodulin: a bifunctional modulator of inflammation and coagulation in sepsis.Why patients with THBD c.1611C>A (p.Cys537X) nonsense mutation have high levels of soluble thrombomodulin?Protein C supports platelet binding and activation under flow: role of glycoprotein Ib and apolipoprotein E receptor 2.Probing the Dynamics of Clot-Bound Thrombin at Venous Shear Rates.The Role of Gap Junction-Mediated Endothelial Cell-Cell Interaction in the Crosstalk between Inflammation and Blood Coagulation.6-Methylsulfinylhexyl isothiocyanate modulates endothelial cell function and suppresses leukocyte adhesion.Differential regulation of protein subdomain activity with caged bivalent ligands.Molecular dynamics simulations of aptamer-binding reveal generalized allostery in thrombin.
P2860
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P2860
Thrombin-cofactor interactions: structural insights into regulatory mechanisms.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
2006年學術文章
@zh
2006年學術文章
@zh-hant
name
Thrombin-cofactor interactions: structural insights into regulatory mechanisms.
@ast
Thrombin-cofactor interactions: structural insights into regulatory mechanisms.
@en
type
label
Thrombin-cofactor interactions: structural insights into regulatory mechanisms.
@ast
Thrombin-cofactor interactions: structural insights into regulatory mechanisms.
@en
prefLabel
Thrombin-cofactor interactions: structural insights into regulatory mechanisms.
@ast
Thrombin-cofactor interactions: structural insights into regulatory mechanisms.
@en
P1476
Thrombin-cofactor interactions: structural insights into regulatory mechanisms.
@en
P2093
James A Huntington
Ty E Adams
P304
P356
10.1161/01.ATV.0000228844.65168.D1
P407
P577
2006-05-25T00:00:00Z