A human liver microphysiology platform for investigating physiology, drug safety, and disease models
about
Advancing cardiovascular tissue engineeringFluorescent protein biosensors applied to microphysiological systemsFacilitating the commercialization and use of organ platforms generated by the microphysiological systems (Tissue Chip) program through public-private partnershipsTranslational Prospects and Challenges in Human Induced Pluripotent Stem Cell Research in Drug DiscoveryKey Challenges and Opportunities Associated with the Use of In Vitro Models to Detect Human DILI: Integrated Risk Assessment and Mitigation PlansAdvances in Engineered Liver Models for Investigating Drug-Induced Liver InjuryMicrophysiological Systems ("Organs-on-Chips") for Drug Efficacy and Toxicity Testing.Functional Coupling of Human Microphysiology Systems: Intestine, Liver, Kidney Proximal Tubule, Blood-Brain Barrier and Skeletal Muscle.Tissue chips - innovative tools for drug development and disease modeling.Microengineered cultures containing human hepatic stellate cells and hepatocytes for drug development.Organs-on-chips: Progress, challenges, and future directions.Human biology-based drug safety evaluation: scientific rationale, current status and future challenges.Liver and Kidney on Chips: Microphysiological Models to Understand Transporter Function.Liver metastases: Microenvironments and ex-vivo models.Tissue Chips to aid drug development and modeling for rare diseases.Engineered Liver Platforms for Different Phases of Drug Development.Recent lab-on-chip developments for novel drug discovery.A Pathway to Personalizing Therapy for Metastases Using Liver-on-a-Chip Platforms.Scaffold-free 3D bio-printed human liver tissue stably maintains metabolic functions useful for drug discovery.Microtechnology-Based Multi-Organ Models.The Microphysiology Systems Database for Analyzing and Modeling Compound Interactions with Human and Animal Organ Models.Modeling Therapeutic Antibody-Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform.A perfusion incubator liver chip for 3D cell culture with application on chronic hepatotoxicity testing.Pathology, proteomics and the pathway to personalised medicine.Liver 'organ on a chip'.Circadian hormone control in a human-on-a-chip: In vitro biology's ignored component?Organ-On-A-Chip Platforms: A Convergence of Advanced Materials, Cells, and Microscale Technologies.Organ-on-a-Chip Systems for Women's Health Applications.Organ-on-a-Chip Technology for Reproducing Multiorgan Physiology.Microphysiological Systems (Tissue Chips) and their Utility for Rare Disease Research.A Cell Culture Platform to Maintain Long-term Phenotype of Primary Human Hepatocytes and Endothelial Cells.Translating scientific discovery: the need for preclinical models of nonalcoholic steatohepatitis.Bioengineered humanized livers as better three-dimensional drug testing model system.A pumpless multi-organ-on-a-chip (MOC) combined with a pharmacokinetic-pharmacodynamic (PK-PD) model.Control of oxygen tension recapitulates zone-specific functions in human liver microphysiology systems.Bioengineered Liver Models for Drug Testing and Cell Differentiation Studies.Tissue engineering toward organ-specific regeneration and disease modeling.3D cellular invasion platforms: how do paper-based cultures stack up?Adhesion analysis of single circulating tumor cells on a base layer of endothelial cells using open microfluidicsCell Migration Research Based on Organ-on-Chip-Related Approaches
P2860
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P2860
A human liver microphysiology platform for investigating physiology, drug safety, and disease models
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年学术文章
@wuu
2015年学术文章
@zh-cn
2015年学术文章
@zh-hans
2015年学术文章
@zh-my
2015年学术文章
@zh-sg
2015年學術文章
@yue
2015年學術文章
@zh
2015年學術文章
@zh-hant
name
A human liver microphysiology ...... rug safety, and disease models
@ast
A human liver microphysiology ...... rug safety, and disease models
@en
type
label
A human liver microphysiology ...... rug safety, and disease models
@ast
A human liver microphysiology ...... rug safety, and disease models
@en
prefLabel
A human liver microphysiology ...... rug safety, and disease models
@ast
A human liver microphysiology ...... rug safety, and disease models
@en
P2093
P2860
P50
P356
P1476
A human liver microphysiology ...... rug safety, and disease models
@en
P2093
Nina Senutovitch
Richard DeBiasio
Robert Boltz
Tong Ying Shun
P2860
P304
P356
10.1177/1535370215592121
P577
2015-07-22T00:00:00Z