Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS
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Harmine, a natural beta-carboline alkaloid, upregulates astroglial glutamate transporter expressionXBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagyAblation of proliferating cells in the CNS exacerbates motor neuron disease caused by mutant superoxide dismutaseHuman glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALSGene delivery to the spinal cord using MRI-guided focused ultrasoundIntravenous administration of self-complementary AAV9 enables transgene delivery to adult motor neurons.Viral vectors for neurotrophic factor delivery: a gene therapy approach for neurodegenerative diseases of the CNSModerate exercise delays the motor performance decline in a transgenic model of ALS.Neurotrophic growth factors for the treatment of amyotrophic lateral sclerosis: where do we stand?Neuroprotection for amyotrophic lateral sclerosis: role of stem cells, growth factors, and gene therapy.AAV4-mediated expression of IGF-1 and VEGF within cellular components of the ventricular system improves survival outcome in familial ALS miceCNS-targeted viral delivery of G-CSF in an animal model for ALS: improved efficacy and preservation of the neuromuscular unitMotor neuron trophic factors: therapeutic use in ALS?Sponge-mediated lentivirus delivery to acute and chronic spinal cord injuries.Intraspinal cell transplantation for targeting cervical ventral horn in amyotrophic lateral sclerosis and traumatic spinal cord injury.Recent advances in amyotrophic lateral sclerosis research: perspectives for personalized clinical applicationMicroNeurotrophins Improve Survival in Motor Neuron-Astrocyte Co-Cultures but Do Not Improve Disease Phenotypes in a Mutant SOD1 Mouse Model of Amyotrophic Lateral Sclerosis.Motor neuron-immune interactions: the vicious circle of ALS.αCAR IGF-1 vector targeting of motor neurons ameliorates disease progression in ALS mice.Delivery of AAV-IGF-1 to the CNS extends survival in ALS mice through modification of aberrant glial cell activity.Dysregulation of the complement cascade in the hSOD1G93A transgenic mouse model of amyotrophic lateral sclerosis.Stem cells: comprehensive treatments for amyotrophic lateral sclerosis in conjunction with growth factor delivery.Antioxidant gene therapy against neuronal cell death.Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis.Research advances in gene therapy approaches for the treatment of amyotrophic lateral sclerosis.Immune-mediated mechanisms in the pathoprogression of amyotrophic lateral sclerosis.Current developments in gene therapy for amyotrophic lateral sclerosis.Adeno-Associated Virus-Based Gene Therapy for CNS Diseases.Potential new complication in drug therapy development for amyotrophic lateral sclerosis.Polyethylene glycol-coupled IGF1 delays motor function defects in a mouse model of spinal muscular atrophy with respiratory distress type 1.Potential for promoting recurrent laryngeal nerve regeneration by remote delivery of viral gene therapy.Intrathecal Delivery of ssAAV9-DAO Extends Survival in SOD1G93A ALS Mice.Connexin 43 in astrocytes contributes to motor neuron toxicity in amyotrophic lateral sclerosis.Intramuscular Injections Along the Motor End Plates: A Minimally Invasive Approach to Shuttle Tracers Directly into Motor NeuronsRobust spinal motor neuron transduction following intrathecal delivery of AAV9 in pigs.Functional improvement in mouse models of familial amyotrophic lateral sclerosis by PEGylated insulin-like growth factor I treatment depends on disease severity.Motor Neuron Gene Therapy: Lessons from Spinal Muscular Atrophy for Amyotrophic Lateral Sclerosis.Vitamin D and Neurological Diseases: An Endocrine View.AAV gene delivery to the spinal cord: serotypes, methods, candidate diseases, and clinical trials.RNS60 exerts therapeutic effects in the SOD1 ALS mouse model through protective glia and peripheral nerve rescue.
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P2860
Intraparenchymal spinal cord delivery of adeno-associated virus IGF-1 is protective in the SOD1G93A model of ALS
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
@wuu
2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
@yue
2007年學術文章
@zh
2007年學術文章
@zh-hant
name
Intraparenchymal spinal cord d ...... e in the SOD1G93A model of ALS
@ast
Intraparenchymal spinal cord d ...... e in the SOD1G93A model of ALS
@en
type
label
Intraparenchymal spinal cord d ...... e in the SOD1G93A model of ALS
@ast
Intraparenchymal spinal cord d ...... e in the SOD1G93A model of ALS
@en
prefLabel
Intraparenchymal spinal cord d ...... e in the SOD1G93A model of ALS
@ast
Intraparenchymal spinal cord d ...... e in the SOD1G93A model of ALS
@en
P2093
P2860
P1433
P1476
Intraparenchymal spinal cord d ...... e in the SOD1G93A model of ALS
@en
P2093
Angelo C Lepore
Christine Haenggeli
Jeffrey D Rothstein
Kathie M Bishop
Mehdi Gasmi
Nicholas J Maragakis
Raymond T Bartus
P2860
P304
P356
10.1016/J.BRAINRES.2007.09.034
P407
P577
2007-09-22T00:00:00Z