Impaired response to GM-CSF and G-CSF, and enhanced apoptosis in C/EBPbeta-deficient hematopoietic cells
about
C/EBP-beta regulates endoplasmic reticulum stress-triggered cell death in mouse and human modelsIn vivo deficiency of both C/EBPβ and C/EBPε results in highly defective myeloid differentiation and lack of cytokine response.Inflammation triggers emergency granulopoiesis through a density-dependent feedback mechanism.Cyclic AMP responsive element binding proteins are involved in 'emergency' granulopoiesis through the upregulation of CCAAT/enhancer binding protein βC/EBPβ promotes BCR-ABL-mediated myeloid expansion and leukemic stem cell exhaustion.Non-steady-state hematopoiesis regulated by the C/EBPβ transcription factor.NETosis and NADPH oxidase: at the intersection of host defense, inflammation, and injury.Effects of 5-fluorouracil chemotherapy on fatigue: role of MCP-1.Regulation of the MAD1 promoter by G-CSF.GM-CSF treatment is not effective in congenital neutropenia patients due to its inability to activate NAMPT signaling.Frontline Science: Myeloid cell-specific deletion of Cebpb decreases sepsis-induced immunosuppression in mice.C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal eventJMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML
P2860
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P2860
Impaired response to GM-CSF and G-CSF, and enhanced apoptosis in C/EBPbeta-deficient hematopoietic cells
description
2007 nî lūn-bûn
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2007年の論文
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年学术文章
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2007年學術文章
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name
Impaired response to GM-CSF an ...... -deficient hematopoietic cells
@ast
Impaired response to GM-CSF an ...... -deficient hematopoietic cells
@en
type
label
Impaired response to GM-CSF an ...... -deficient hematopoietic cells
@ast
Impaired response to GM-CSF an ...... -deficient hematopoietic cells
@en
prefLabel
Impaired response to GM-CSF an ...... -deficient hematopoietic cells
@ast
Impaired response to GM-CSF an ...... -deficient hematopoietic cells
@en
P2093
P2860
P1433
P1476
Impaired response to GM-CSF an ...... -deficient hematopoietic cells
@en
P2093
Adrian F Gombart
H Phillip Koeffler
James O'Kelly
Shizuo Akira
Tadayuki Akagi
Takayuki Saitoh
P2860
P304
P356
10.1182/BLOOD-2007-04-087213
P407
P577
2007-12-04T00:00:00Z