The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.
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TCEAL7, a putative tumor suppressor gene, negatively regulates NF-kappaB pathwayThe Mesothelial Origin of Carcinoma Associated-Fibroblasts in Peritoneal MetastasisRole of mesenchymal cells in the natural history of ovarian cancer: a reviewMolecular pathways: trafficking of metabolic resources in the tumor microenvironmentCell-cell and cell-matrix dynamics in intraperitoneal cancer metastasisThe hemodynamically-regulated vascular microenvironment promotes migration of the steroidogenic tissue during its interaction with chromaffin cells in the zebrafish embryoRole of surface chemistry in protein remodeling at the cell-material interfaceDiscovery of specific metastasis-related N-glycan alterations in epithelial ovarian cancer based on quantitative glycomicsOvarian cancer spheroids use myosin-generated force to clear the mesotheliumS1PR1-STAT3 signaling is crucial for myeloid cell colonization at future metastatic sites.Ovarian tumor attachment, invasion, and vascularization reflect unique microenvironments in the peritoneum: insights from xenograft and mathematical models.PDGF‑stimulated dispersal of cell clusters and disruption of fibronectin matrix on three-dimensional collagen matrices requires matrix metalloproteinase-2.Alterations in ovarian cancer cell adhesion drive taxol resistance by increasing microtubule dynamics in a FAK-dependent manner.The Extracellular Matrix in Epithelial Ovarian Cancer - A Piece of a Puzzle.Identification of a novel small molecule HIF-1alpha translation inhibitor.Cyr61/CCN1 displays high-affinity binding to the somatomedin B(1-44) domain of vitronectin.Altered gene expression in morphologically normal epithelial cells from heterozygous carriers of BRCA1 or BRCA2 mutationsAn orally available small-molecule inhibitor of c-Met, PF-2341066, reduces tumor burden and metastasis in a preclinical model of ovarian cancer metastasis.37-kDa laminin receptor precursor mediates GnRH-II-induced MMP-2 expression and invasiveness in ovarian cancer cells.Preclinical therapeutic potential of a nitrosylating agent in the treatment of ovarian cancer.MUC16 (CA125): tumor biomarker to cancer therapy, a work in progressMMP-2 functions as an early response protein in ovarian cancer metastasisEpidermal growth factor receptor-mediated membrane type 1 matrix metalloproteinase endocytosis regulates the transition between invasive versus expansive growth of ovarian carcinoma cells in three-dimensional collagenVersican regulates metastasis of epithelial ovarian carcinoma cells and spheroids.Integrated analysis of multiple microarray datasets identifies a reproducible survival predictor in ovarian cancer.Longitudinal measurement of extracellular matrix rigidity in 3D tumor models using particle-tracking microrheology.Activation of the PKC pathway stimulates ovarian cancer cell proliferation, migration, and expression of MMP7 and MMP10.Mesenchymal cell interaction with ovarian cancer cells induces a background dependent pro-metastatic transcriptomic profile.Conditionally replicating adenovirus expressing TIMP2 increases survival in a mouse model of disseminated ovarian cancerOvarian cancer development and metastasis.Fibronectin affects transient MMP2 gene expression through DNA demethylation changes in non-invasive breast cancer cell lines.Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion.MMP2 and acrosin are major proteinases associated with the inner acrosomal membrane and may cooperate in sperm penetration of the zona pellucida during fertilization.Assessment of ovarian cancer spheroid attachment and invasion of mesothelial cells in real time.Matrix metalloproteinase-2 promotes αvβ3 integrin-mediated adhesion and migration of human melanoma cells by cleaving fibronectin.Deciphering the ovarian cancer ascites fluid peptidome.TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival.Targeting the urokinase plasminogen activator receptor inhibits ovarian cancer metastasis.Role of versican, hyaluronan and CD44 in ovarian cancer metastasis.Myocardial matrix metalloproteinase-2: inside out and upside down.
P2860
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P2860
The initial steps of ovarian cancer cell metastasis are mediated by MMP-2 cleavage of vitronectin and fibronectin.
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
The initial steps of ovarian c ...... f vitronectin and fibronectin.
@ast
The initial steps of ovarian c ...... f vitronectin and fibronectin.
@en
type
label
The initial steps of ovarian c ...... f vitronectin and fibronectin.
@ast
The initial steps of ovarian c ...... f vitronectin and fibronectin.
@en
prefLabel
The initial steps of ovarian c ...... f vitronectin and fibronectin.
@ast
The initial steps of ovarian c ...... f vitronectin and fibronectin.
@en
P2093
P2860
P356
P1476
The initial steps of ovarian c ...... of vitronectin and fibronectin
@en
P2093
Hilary A Kenny
Lisa M Coussens
Swayamjot Kaur
P2860
P304
P356
10.1172/JCI33775
P407
P577
2008-04-01T00:00:00Z