DCPIB, the proposed selective blocker of volume-regulated anion channels, inhibits several glutamate transport pathways in glial cells.
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Comparative Effects of Chloride Channel Inhibitors on LRRC8/VRAC-Mediated Chloride Conductance.LRRC8A protein is indispensable for swelling-activated and ATP-induced release of excitatory amino acids in rat astrocytes.Volume-regulated anion channel--a frenemy within the brain.The neuroprotective properties of the superoxide dismutase mimetic tempol correlate with its ability to reduce pathological glutamate release in a rodent model of stroke.Osmotic Edema Rapidly Increases Neuronal Excitability Through Activation of NMDA Receptor-Dependent Slow Inward Currents in Juvenile and Adult HippocampusIntracellular levels of glutamate in swollen astrocytes are preserved via neurotransmitter reuptake and de novo synthesis: implications for hyponatremia.LRRC8A channels support TNFα-induced superoxide production by Nox1 which is required for receptor endocytosis.The identification of a volume-regulated anion channel: an amazing Odyssey.Astrocyte calcium waves propagate proximally by gap junction and distally by extracellular diffusion of ATP released from volume-regulated anion channels.Molecular composition and heterogeneity of the LRRC8-containing swelling-activated osmolyte channels in primary rat astrocytes.Thrombin-facilitated efflux of D-[3H]-aspartate from cultured astrocytes and neurons under hyponatremia and chemical ischemia.LRRC8/VRAC anion channels enhance β-cell glucose sensing and insulin secretion.
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DCPIB, the proposed selective blocker of volume-regulated anion channels, inhibits several glutamate transport pathways in glial cells.
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2012 nî lūn-bûn
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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name
DCPIB, the proposed selective ...... sport pathways in glial cells.
@ast
DCPIB, the proposed selective ...... sport pathways in glial cells.
@en
type
label
DCPIB, the proposed selective ...... sport pathways in glial cells.
@ast
DCPIB, the proposed selective ...... sport pathways in glial cells.
@en
prefLabel
DCPIB, the proposed selective ...... sport pathways in glial cells.
@ast
DCPIB, the proposed selective ...... sport pathways in glial cells.
@en
P2093
P2860
P356
P1476
DCPIB, the proposed selective ...... sport pathways in glial cells.
@en
P2093
Alexander A Mongin
Nicole H Bowens
Preeti Dohare
Yu-Hung Kuo
P2860
P356
10.1124/MOL.112.080457
P577
2012-09-25T00:00:00Z