Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance. - Wikidata - awgldk - TriplyDB

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.

http://www.wikidata.org/entity/Q36498043

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Signaling from axon guidance receptors Microtubule plus-end tracking proteins in neuronal development Function and regulation of the Rho guanine nucleotide exchange factor Trio The Rac GTP exchange factor TIAM-1 acts with CDC-42 and the guidance receptor UNC-40/DCC in neuronal protrusion and axon guidance Echovirus 30 induced neuronal cell death through TRIO-RhoA signaling activation Regulation of Kalirin by Cdk5 The RhoGEF DOCK10 is essential for dendritic spine morphogenesis p120RasGAP Protein Mediates Netrin-1 Protein-induced Cortical Axon Outgrowth and Guidance.Tyrosine phosphorylation of Rac1: a role in regulation of cell spreading Trio is a key guanine nucleotide exchange factor coordinating regulation of the migration and morphogenesis of granule cells in the developing cerebellum.Calcineurin-dependent cofilin activation and increased retrograde actin flow drive 5-HT-dependent neurite outgrowth in Aplysia bag cell neurons.Actin dynamics in growth cone motility and navigation The UNC-6/Netrin receptors UNC-40/DCC and UNC-5 inhibit growth cone filopodial protrusion via UNC-73/Trio, Rac-like GTPases and UNC-33/CRMP.Axon guidance: asymmetric signaling orients polarized outgrowth.Cellular responses to extracellular guidance cues The growth cone: an integrator of unique cues into refined axon guidance Regulation of promyogenic signal transduction by cell-cell contact and adhesion.Disabled is a bona fide component of the Abl signaling network.Identification of a mitotic Rac-GEF, Trio, that counteracts MgcRacGAP function during cytokinesis Roles for netrin signaling outside of axon guidance: a view from the worm The SAX-3 receptor stimulates axon outgrowth and the signal sequence and transmembrane domain are critical for SAX-3 membrane localization in the PDE neuron of C. elegans.Disrupted-in-Schizophrenia 1-mediated axon guidance involves TRIO-RAC-PAK small GTPase pathway signaling Second messengers and membrane trafficking direct and organize growth cone steering.The activation of ezrin-radixin-moesin proteins is regulated by netrin-1 through Src kinase and RhoA/Rho kinase activities and mediates netrin-1-induced axon outgrowth.A Trio-RhoA-Shroom3 pathway is required for apical constriction and epithelial invagination Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.Hsc70 chaperone activity underlies Trio GEF function in axon growth and guidance induced by netrin-1.FLIM FRET Visualization of Cdc42 Activation by Netrin-1 in Embryonic Spinal Commissural Neuron Growth Cones Down syndrome cell adhesion molecule (DSCAM) associates with uncoordinated-5C (UNC5C) in netrin-1-mediated growth cone collapse.Rho GTPases in embryonic development Crk adaptor proteins act as key signaling integrators for breast tumorigenesis c-Jun N-terminal kinase 1 (JNK1) is required for coordination of netrin signaling in axon guidance.TRIO loss of function is associated with mild intellectual disability and affects dendritic branching and synapse function.Tyrosine phosphorylation of the Rho guanine nucleotide exchange factor Trio regulates netrin-1/DCC-mediated cortical axon outgrowth Long-Term Memory in Drosophila Is Influenced by Histone Deacetylase HDAC4 Interacting with SUMO-Conjugating Enzyme Ubc9.Axon growth and guidance: receptor regulation and signal transduction Neuronal Rho GEFs in synaptic physiology and behavior.Mutations specific to the Rac-GEF domain of TRIO cause intellectual disability and microcephaly.Rho and Ras GTPases in axon growth, guidance, and branching.Synaptic plasticity, a symphony in GEF.

P2860

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P2860

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.

http://www.wikidata.org/entity/Q36498043

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.

@ast

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.

@en

type

label

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.

@ast

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.

@en

prefLabel

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.

@ast

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance.

@en

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P1433

Molecular and Cellular Biology

P1476

Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance

@en

P2093

Anne Debant

http://www.w3.org/2001/XMLSchema#string

Atefeh Ghogha

http://www.w3.org/2001/XMLSchema#string

Camille Auziol

http://www.w3.org/2001/XMLSchema#string

Chantal Piché

http://www.w3.org/2001/XMLSchema#string

Hervé Enslen

http://www.w3.org/2001/XMLSchema#string

Ibtissem Triki

http://www.w3.org/2001/XMLSchema#string

Jean-François Cloutier

http://www.w3.org/2001/XMLSchema#string

Karim Chebli

http://www.w3.org/2001/XMLSchema#string

Nathalie Lamarche-Vane

http://www.w3.org/2001/XMLSchema#string

Sylvie Fromont

http://www.w3.org/2001/XMLSchema#string

P2860

Deleted in Colorectal Cancer (DCC) encodes a netrin receptor

The multidomain protein Trio binds the LAR transmembrane tyrosine phosphatase, contains a protein kinase domain, and has separate rac-specific and rho-specific guanine nucleotide exchange factor domains

Multiple signaling mechanisms of the UNC-6/netrin receptors UNC-5 and UNC-40/DCC in vivo

The dependence receptor UNC5H2 mediates apoptosis through DAP-kinase

Vertebrate homologues of C. elegans UNC-5 are candidate netrin receptors

TrioGEF1 controls Rac- and Cdc42-dependent cell structures through the direct activation of rhoG

The Human Rho-GEF trio and its target GTPase RhoG are involved in the NGF pathway, leading to neurite outgrowth

Phenotype of mice lacking functional Deleted in colorectal cancer (Dcc) gene

The two guanine nucleotide exchange factor domains of Trio link the Rac1 and the RhoA pathways in vivo

Focal adhesion kinase in netrin-1 signaling

P304

2314-2323

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P31

scholarly article

P356

10.1128/MCB.00998-07

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P407

P433

7

http://www.w3.org/2001/XMLSchema#string

P478

28

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P50

Valérie Castellani

Anne Briançon-Marjollet

P577

2008-01-22T00:00:00Z

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P698

18212043

http://www.w3.org/2001/XMLSchema#string

P932

2268419

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