Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity - Wikidata - awgldk - TriplyDB

Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity

Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity

http://www.wikidata.org/entity/Q36498064

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Janus kinases in immune cell signaling Tyrosines 868, 966, and 972 in the kinase domain of JAK2 are autophosphorylated and required for maximal JAK2 kinase activity Survey of phosphorylation near drug binding sites in the Protein Data Bank (PDB) and their effects.Protein phosphatase 2A regulates interleukin-2 receptor complex formation and JAK3/STAT5 activation.Janus kinase 3: the controller and the controlled Signal transducer and activator of transcription 5b (Stat5b) serine 193 is a novel cytokine-induced phospho-regulatory site that is constitutively activated in primary hematopoietic malignancies.Interleukin-2 Receptor β Thr-450 Phosphorylation Is a Positive Regulator for Receptor Complex Stability and Activation of Signaling Molecules.Forskolin-inducible cAMP pathway negatively regulates T-cell proliferation by uncoupling the interleukin-2 receptor complex.Potential molecular mechanism for c-Src kinase-mediated regulation of intestinal cell migration.JAK inhibitor tofacitinib for treating rheumatoid arthritis: from basic to clinical.Clinical utility of the oral JAK inhibitor tofacitinib in the treatment of rheumatoid arthritis.Qualitatively different T cell phenotypic responses to IL-2 versus IL-15 are unified by identical dependences on receptor signal strength and duration.Development of a high-throughput cell-based reporter assay for screening of JAK3 inhibitors.Transforming Mutations of Jak3 (A573V and M511I) Show Differential Sensitivity to Selective Jak3 Inhibitors.IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3

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Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity

http://www.wikidata.org/entity/Q36498064

description

2008 nî lūn-bûn

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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2008年學術文章

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2008年學術文章

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name

Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity

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Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity

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type

label

Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity

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Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity

@en

prefLabel

Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity

@ast

Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity

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Molecular and Cellular Biology

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Phosphorylation of human Jak3 at tyrosines 904 and 939 positively regulates its activity

@en

P2093

Hanyin Cheng

http://www.w3.org/2001/XMLSchema#string

Jeffrey A Frost

http://www.w3.org/2001/XMLSchema#string

Jeremy A Ross

http://www.w3.org/2001/XMLSchema#string

Robert A Kirken

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P2860

CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling

The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3

Molecular cloning of L-JAK, a Janus family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes

Regulation of JAK3 expression and activation in human B cells and B cell malignancies

Identification, cDNA cloning, and targeted deletion of p70, a novel, ubiquitously expressed SH3 domain-containing protein.

Activation of Jak2 catalytic activity requires phosphorylation of Y1007 in the kinase activation loop

ELM server: A new resource for investigating short functional sites in modular eukaryotic proteins

Regulation of JAK3 expression in human monocytes: phosphorylation in response to interleukins 2, 4, and 7

Crystal structure of the tyrosine kinase domain of the human insulin receptor

Autophosphorylation of JAK2 on tyrosines 221 and 570 regulates its activity

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2271-2282

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scholarly article

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10.1128/MCB.01789-07

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7

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28

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2008-02-04T00:00:00Z

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5602540

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18250158

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phosphorylation

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2268424

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