Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function
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Interleukin-32 promotes osteoclast differentiation but not osteoclast activationEvolutionary divergence and functions of the human interleukin (IL) gene familyInterleukin-32δ interacts with IL-32β and inhibits IL-32β-mediated IL-10 productionBone Marrow Immunity and MyelodysplasiaMesenchymal Stem and Progenitor Cells in Normal and Dysplastic Hematopoiesis-Masters of Survival and Clonality?Infections in myelodysplastic syndromesRecent advances in diagnosis, molecular pathology and therapy of chronic myelomonocytic leukaemiaInterleukin 32 (IL-32) contains a typical α-helix bundle structure that resembles focal adhesion targeting region of focal adhesion kinase-1.IL-32 promotes angiogenesis.Identification of DJ-1/PARK-7 as a determinant of stroma-dependent and TNF-alpha-induced apoptosis in MDS using mass spectrometry and phosphopeptide analysis.Myeloid Malignancies and the Marrow Microenvironment: Some Recent Studies in Patients with MDSThe helix-loop-helix transcription factor TWIST is dysregulated in myelodysplastic syndromes.Dietary blue pigments derived from genipin, attenuate inflammation by inhibiting LPS-induced iNOS and COX-2 expression via the NF-κB inactivation.Inflammation-dependent secretion and splicing of IL-32{gamma} in rheumatoid arthritis.Overexpression of IL-32alpha increases natural killer cell-mediated killing through up-regulation of Fas and UL16-binding protein 2 (ULBP2) expression in human chronic myeloid leukemia cells.IL-32γ inhibits cancer cell growth through inactivation of NF-κB and STAT3 signals.Inhibition of IL-32 activation by α-1 antitrypsin suppresses alloreactivity and increases survival in an allogeneic murine marrow transplantation model.Biology of BM failure syndromes: role of microenvironment and niches.The anti-inflammatory activities of ethanol extract from Dan-Lou prescription in vivo and in vitro.NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy.Overexpression of IL-32 is a novel prognostic factor in patients with localized clear cell renal cell carcinomaDNA methylation and gene expression profiling of ewing sarcoma primary tumors reveal genes that are potential targets of epigenetic inactivation.Five-group cytogenetic risk classification, monosomal karyotype, and outcome after hematopoietic cell transplantation for MDS or acute leukemia evolving from MDS.Stroma-dependent apoptosis in clonal hematopoietic precursors correlates with expression of PYCARD.IL-32-dependent effects of IL-1beta on endothelial cell functionsNo telomere shortening in marrow stroma from patients with MDS.Molecular characterization of IL-32 in human endothelial cellsModeling human hematopoietic stem cell biology in the mouse.Therapeutic targeting of microenvironmental interactions in leukemia: mechanisms and approaches.De novo AML exhibits greater microenvironment dysregulation compared to AML with myelodysplasia-related changes.Interleukin-32α induces migration of human melanoma cells through downregulation of E-cadherin.Leukemia stem cells and microenvironment: biology and therapeutic targeting.Immune alterations in untreated and treated myelodysplastic syndrome.Role of immune responses in the pathogenesis of low-risk MDS and high-risk MDS: implications for immunotherapy.Molecular biology of myelodysplastic syndromes.Myelodysplastic syndromes: revisiting the role of the bone marrow microenvironment in disease pathogenesis.Role of interleukin-32 in chronic rhinosinusitisNovel insights into the biology of interleukin-32.An evolutionary perspective on chronic myelomonocytic leukemia.Chronic myelomonocytic leukemia prognostic classification and management: evidence base and current practice.
P2860
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P2860
Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
2008年學術文章
@zh
2008年學術文章
@zh-hant
name
Dysregulation of IL-32 in myel ...... ptosis and impairs NK function
@ast
Dysregulation of IL-32 in myel ...... ptosis and impairs NK function
@en
type
label
Dysregulation of IL-32 in myel ...... ptosis and impairs NK function
@ast
Dysregulation of IL-32 in myel ...... ptosis and impairs NK function
@en
prefLabel
Dysregulation of IL-32 in myel ...... ptosis and impairs NK function
@ast
Dysregulation of IL-32 in myel ...... ptosis and impairs NK function
@en
P2093
P2860
P356
P1476
Dysregulation of IL-32 in myel ...... ptosis and impairs NK function
@en
P2093
A Mario Marcondes
Andrew J Mhyre
Derek L Stirewalt
Soo-Hyun Kim
P2860
P304
P356
10.1073/PNAS.0712391105
P407
P577
2008-02-19T00:00:00Z