Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice

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Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice

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2016 nî lūn-bûn

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2016年の論文

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2016年論文

@yue

2016年論文

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2016年論文

@zh-hk

2016年論文

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2016年論文

@zh-tw

2016年论文

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2016年论文

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2016年论文

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Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice

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Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice

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Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice

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Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice

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Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice

@ast

Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice

@en

P1476

Oncogenic potential of IDH1R132C mutant in cholangiocarcinoma development in mice

@en

P2093

Biao Fan

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Jun-Yan Tao

http://www.w3.org/2001/XMLSchema#string

Li Che

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Li-Jie Jiang

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Ning Ding

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Xiao-Lei Li

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Xin Chen

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Yan Liu

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P2860

Hallmarks of Cancer: The Next Generation

Identification and functional characterization of isocitrate dehydrogenase 1 (IDH1) mutations in thyroid cancer

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

Recurring mutations found by sequencing an acute myeloid leukemia genome

An integrated genomic analysis of human glioblastoma multiforme

Genetic heterogeneity in cholangiocarcinoma: a major challenge for targeted therapies

Cholangiocarcinoma

P304

2071-2080

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P31

scholarly article

P356

10.3748/WJG.V22.I6.2071

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P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

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P50

Jiafu Ji

P577

2016-02-01T00:00:00Z

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P5875

292187719

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P698

26877611

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P921

cholangiocarcinoma

P932

4726679

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