iPLA2beta: front and center in human monocyte chemotaxis to MCP-1
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Moving towards a paradigm: common mechanisms of chemotactic signaling in Dictyostelium and mammalian leukocytesPhospholipase A2 enzymes: physical structure, biological function, disease implication, chemical inhibition, and therapeutic interventionDecreased peritoneal ovarian cancer growth in mice lacking expression of lipid phosphate phosphohydrolase 1.Role of molecular determinants of store-operated Ca(2+) entry (Orai1, phospholipase A2 group 6, and STIM1) in focal adhesion formation and cell migration.Group VIA Ca2+-independent phospholipase A2 (iPLA2beta) and its role in beta-cell programmed cell death.Aiming drug discovery at lysophosphatidic acid targets.Lipid rafts couple class A scavenger receptors to phospholipase A2 activation during macrophage adhesion.The phospholipase A1 activity of lysophospholipase A-I links platelet activation to LPA production during blood coagulationRole of iPLA(2) in the regulation of Src trafficking and microglia chemotaxis.Analysis of two major intracellular phospholipases A(2) (PLA(2)) in mast cells reveals crucial contribution of cytosolic PLA(2)α, not Ca(2+)-independent PLA(2)β, to lipid mobilization in proximal mast cells and distal fibroblasts.The WD40 repeat protein WDR26 binds Gβγ and promotes Gβγ-dependent signal transduction and leukocyte migrationEmergence of a metalloproteinase / phospholipase A2 axis of systemic inflammation.Deficiency of iPLA₂β Primes Immune Cells for Proinflammation: Potential Involvement in Age-Related Mesenteric Lymph Node LymphomaMetabolic products of soluble epoxide hydrolase are essential for monocyte chemotaxis to MCP-1 in vitro and in vivo.Mice with Genetic Deletion of Group VIA Phospholipase A2β Exhibit Impaired Macrophage Function and Increased Parasite Load in Trypanosoma cruzi-Induced Myocarditis.Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitisPhospholipase A2 structure/function, mechanism, and signaling.Signal-activated phospholipase regulation of leukocyte chemotaxisTransmigration across activated endothelium induces transcriptional changes, inhibits apoptosis, and decreases antimicrobial protein expression in human monocytes.The autotaxin-LPA axis emerges as a novel regulator of lymphocyte homing and inflammation.Group VIA phospholipase A2 mediates enhanced macrophage migration in diabetes mellitus by increasing expression of nicotinamide adenine dinucleotide phosphate oxidase 4.Regulation of Integrin α6 Recycling by Calcium-independent Phospholipase A2 (iPLA2) to Promote Microglia Chemotaxis on Laminin.Modulation of Systemic Metabolism by MMP-2: From MMP-2 Deficiency in Mice to MMP-2 Deficiency in Patients.Signaling Pathways Controlling Microglia Chemotaxis.Diverse regulation of retinal pigment epithelium phagocytosis of photoreceptor outer segments by calcium-independent phospholipase A₂, group VIA and secretory phospholipase A₂, group IB.HL-1 mouse cardiomyocyte injury and death after simulated ischemia and reperfusion: roles of pH, Ca2+-independent phospholipase A2, and Na+/H+ exchange.Chemokines (CCL3, CCL4, and CCL5) Inhibit ATP-Induced Release of IL-1β by Monocytic CellsP2Y₆ receptor inhibition perturbs CCL2-evoked signalling in human monocytic and peripheral blood mononuclear cellsPolarization of Macrophages toward M2 Phenotype Is Favored by Reduction in iPLA2β (Group VIA Phospholipase A2)Curcumin and enalapril ameliorate renal failure by antagonizing inflammation in 5/6 nephrectomized rats: role of phospholipase and cyclooxygenase.Calcium-independent phospholipase A2 mediates proliferation of human promonocytic U937 cells.
P2860
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P2860
iPLA2beta: front and center in human monocyte chemotaxis to MCP-1
description
2008 nî lūn-bûn
@nan
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
2008年论文
@zh
2008年论文
@zh-cn
name
iPLA2beta: front and center in human monocyte chemotaxis to MCP-1
@ast
iPLA2beta: front and center in human monocyte chemotaxis to MCP-1
@en
type
label
iPLA2beta: front and center in human monocyte chemotaxis to MCP-1
@ast
iPLA2beta: front and center in human monocyte chemotaxis to MCP-1
@en
prefLabel
iPLA2beta: front and center in human monocyte chemotaxis to MCP-1
@ast
iPLA2beta: front and center in human monocyte chemotaxis to MCP-1
@en
P2093
P2860
P356
P1476
iPLA2beta: front and center in human monocyte chemotaxis to MCP-1
@en
P2093
Kevin A Carnevale
Martha K Cathcart
Ravi S Mishra
P2860
P304
P356
10.1084/JEM.20071243
P407
P577
2008-01-21T00:00:00Z