Differential regulation of extracellular tissue inhibitor of metalloproteinases-3 levels by cell membrane-bound and shed low density lipoprotein receptor-related protein 1.
about
LRP-1: a checkpoint for the extracellular matrix proteolysisThe Matricellular Receptor LRP1 Forms an Interface for Signaling and Endocytosis in Modulation of the Extracellular Tumor EnvironmentDevelopment of a monoclonal anti-ADAMTS-5 antibody that specifically blocks the interaction with LRP1.Low-density lipoprotein receptor-related protein-1 mediates endocytic clearance of tissue inhibitor of metalloproteinases-1 and promotes its cytokine-like activitiesSulfated glycosaminoglycans control the extracellular trafficking and the activity of the metalloprotease inhibitor TIMP-3.ADAM10 controls collagen signaling and cell migration on collagen by shedding the ectodomain of discoidin domain receptor 1 (DDR1).Metalloproteinases: a Functional Pathway for Myeloid Cells.Engineered Tissue Inhibitor of Metalloproteinases-3 Variants Resistant to Endocytosis Have Prolonged Chondroprotective Activity.MMP-13 is constitutively produced in human chondrocytes and co-endocytosed with ADAMTS-5 and TIMP-3 by the endocytic receptor LRP1Low density lipoprotein receptor-related protein 1 (LRP1)-mediated endocytic clearance of a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4): functional differences of non-catalytic domains of ADAMTS-4 and ADAMTS-5 in LRP1 bSuramin Inhibits Osteoarthritic Cartilage Degradation by Increasing Extracellular Levels of Chondroprotective Tissue Inhibitor of Metalloproteinases 3.Inhibition of Shedding of Low-Density Lipoprotein Receptor-Related Protein 1 Reverses Cartilage Matrix Degradation in Osteoarthritis.Shedding of membrane-associated LDL receptor-related protein-1 from microglia amplifies and sustains neuroinflammation.Recombinant Expression of the Full-length Ectodomain of LDL Receptor-related Protein 1 (LRP1) Unravels pH-dependent Conformational Changes and the Stoichiometry of Binding with Receptor-associated Protein (RAP).Soluble LRP1 is an independent biomarker of epicardial fat volume in patients with type 1 diabetes mellitus.Interleukin-1 Acts via the JNK-2 Signaling Pathway to Induce Aggrecan Degradation by Human Chondrocytes.LRP1 is required for novobiocin-mediated fibronectin turnoverIncreased TIMP-3 expression alters the cellular secretome through dual inhibition of the metalloprotease ADAM10 and ligand-binding of the LRP-1 receptorUtility of Glycosylated TIMP3 molecules: Inhibition of MMPs and TACE to improve cardiac function in rat myocardial infarct model
P2860
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P2860
Differential regulation of extracellular tissue inhibitor of metalloproteinases-3 levels by cell membrane-bound and shed low density lipoprotein receptor-related protein 1.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Differential regulation of ext ...... in receptor-related protein 1.
@ast
Differential regulation of ext ...... in receptor-related protein 1.
@en
type
label
Differential regulation of ext ...... in receptor-related protein 1.
@ast
Differential regulation of ext ...... in receptor-related protein 1.
@en
prefLabel
Differential regulation of ext ...... in receptor-related protein 1.
@ast
Differential regulation of ext ...... in receptor-related protein 1.
@en
P2093
P2860
P356
P1476
Differential regulation of ext ...... in receptor-related protein 1.
@en
P2093
Dudley K Strickland
Hervé Emonard
Hideaki Nagase
Ida Thøgersen
Jan J Enghild
Kazuhiro Yamamoto
Linda Troeberg
Simone D Scilabra
P2860
P304
P356
10.1074/JBC.M112.393322
P407
P577
2012-11-19T00:00:00Z