Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies. - Wikidata - awgldk - TriplyDB

Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies.

Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies.

http://www.wikidata.org/entity/Q36508970

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Placental origins of adverse pregnancy outcomes: potential molecular targets: an Executive Workshop Summary of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Placental Responses to Changes in the Maternal Environment Determine Fetal Growth Placental Adaptation: What Can We Learn from Birthweight:Placental Weight Ratio?Parturition dysfunction in obesity: time to target the pathobiology Milk--A Nutrient System of Mammalian Evolution Promoting mTORC1-Dependent Translation Inflammation in maternal obesity and gestational diabetes mellitus The role of placental nutrient sensing in maternal-fetal resource allocation The pathogenic role of persistent milk signaling in mTORC1- and milk-microRNA-driven type 2 diabetes mellitus Effects of maternal obesity on placental function and fetal development Placental Metal Concentrations in Relation to Maternal and Infant Toenails in a U.S. Cohort Placental Origins of Chronic Disease.Hypoxia and the anticoagulants dalteparin and acetylsalicylic acid affect human placental amino acid transport.Maternal folate deficiency causes inhibition of mTOR signaling, down-regulation of placental amino acid transporters and fetal growth restriction in mice Insulin Treatment May Alter Fatty Acid Carriers in Placentas from Gestational Diabetes Subjects Increasing maternal body mass index is associated with systemic inflammation in the mother and the activation of distinct placental inflammatory pathways.The potential mechanistic link between allergy and obesity development and infant formula feeding Differential regulation of placental amino acid transport by saturated and unsaturated fatty acids Maternal-fetal nutrient transport in pregnancy pathologies: the role of the placenta Milk consumption during pregnancy increases birth weight, a risk factor for the development of diseases of civilization Maternal obesity is associated with a reduction in placental taurine transporter activity.rpS6 regulates blood-testis barrier dynamics through Arp3-mediated actin microfilament organization in rat sertoli cells. An in vitro study Maternal fuels and metabolic measures during pregnancy and neonatal body composition: the healthy start study.Expression and functional characterisation of System L amino acid transporters in the human term placenta.Maternal High-fat Diet Accelerates Development of Crohn's Disease-like Ileitis in TNFΔARE/WT Offspring.Increased placental nutrient transport in a novel mouse model of maternal obesity with fetal overgrowth.Dietary leucine supplementation minimises tumour-induced damage in placental tissues of pregnant, tumour-bearing rats Adiponectin supplementation in pregnant mice prevents the adverse effects of maternal obesity on placental function and fetal growth.Increased ubiquitination and reduced plasma membrane trafficking of placental amino acid transporter SNAT-2 in human IUGR.TNF-α stimulates System A amino acid transport in primary human trophoblast cells mediated by p38 MAPK signaling Maternal Body Weight and Gestational Diabetes Differentially Influence Placental and Pregnancy Outcomes Morphological and molecular changes in the murine placenta exposed to normobaric hypoxia throughout pregnancy Activation of placental insulin and mTOR signaling in a mouse model of maternal obesity associated with fetal overgrowth.Oleic acid stimulates system A amino acid transport in primary human trophoblast cells mediated by toll-like receptor 4.Discrepancy in Insulin Regulation between Gestational Diabetes Mellitus (GDM) Platelets and Placenta.A Summary of Pathways or Mechanisms Linking Preconception Maternal Nutrition with Birth Outcomes.Role of placental nutrient sensing in developmental programming Maternal and fetal genomes interplay through phosphoinositol 3-kinase(PI3K)-p110α signaling to modify placental resource allocation.Down-regulation of placental mTOR, insulin/IGF-I signaling, and nutrient transporters in response to maternal nutrient restriction in the baboon.Diet-induced obesity in mice reduces placental efficiency and inhibits placental mTOR signaling Maternal obesity is associated with a lipotoxic placental environment.

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P2860

Activation of placental mTOR signaling and amino acid transporters in obese women giving birth to large babies.

http://www.wikidata.org/entity/Q36508970

description

2012 nî lūn-bûn

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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2012年论文

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2012年论文

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Activation of placental mTOR s ...... giving birth to large babies.

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Activation of placental mTOR s ...... giving birth to large babies.

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Activation of placental mTOR s ...... giving birth to large babies.

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Activation of placental mTOR s ...... giving birth to large babies.

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The Journal of Clinical Endocrinology and Metabolism

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Activation of placental mTOR s ...... n giving birth to large babies

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Francesca Gaccioli

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Fredrick J Rosario

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Helen N Jones

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Nina Jansson

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Sara Roos

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Thomas Jansson

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P2860

Involvement of transporter recruitment as well as gene expression in the substrate-induced adaptive regulation of amino acid transport system A.

Maternal obesity is associated with dysregulation of metabolic, vascular, and inflammatory pathways.

Altered activity of the system A amino acid transporter in microvillous membrane vesicles from placentas of macrosomic babies born to diabetic women

Adaptation of nutrient supply to fetal demand in the mouse involves interaction between the Igf2 gene and placental transporter systems.

Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitus.

Fatty acid binding protein 4 regulates intracellular lipid accumulation in human trophoblasts.

Dysregulation of placental endothelial lipase in obese women with gestational diabetes mellitus.

Evidence of placental translation inhibition and endoplasmic reticulum stress in the etiology of human intrauterine growth restriction.

Regulation of placental nutrient transport--a review.

Maternal protein restriction in the rat inhibits placental insulin, mTOR, and STAT3 signaling and down-regulates placental amino acid transporters.

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10.1210/JC.2012-2667

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1

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Theresa L. Powell

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