Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors
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Synthesis and Evaluation of Tricarbonyl (99m)Tc-Labeled 2-(4-Chloro)phenyl-imidazo[1,2-a]pyridine Analogs as Novel SPECT Imaging Radiotracer for TSPO-Rich CancerImaging of atherosclerosisComparison of [(11)C]-(R)-PK 11195 and [(11)C]PBR28, two radioligands for translocator protein (18 kDa) in human and monkey: Implications for positron emission tomographic imaging of this inflammation biomarkerInflammation imaging in atherosclerosisTowards molecular imaging of multiple sclerosis.Cyclooxygenase and neuroinflammation in Parkinson's disease neurodegeneration.In vivo binding of protoporphyrin IX to rat translocator protein imaged with positron emission tomographyCocaine abuse in humans is not associated with increased microglial activation: an 18-kDa translocator protein positron emission tomography imaging study with [11C]PBR28.Two binding sites for [3H]PBR28 in human brain: implications for TSPO PET imaging of neuroinflammation.Biodistribution and radiation dosimetry in humans of a new PET ligand, (18)F-PBR06, to image translocator protein (18 kDa).Synthesis and evaluation of translocator 18 kDa protein (TSPO) positron emission tomography (PET) radioligands with low binding sensitivity to human single nucleotide polymorphism rs6971.Evaluation of novel N1-methyl-2-phenylindol-3-ylglyoxylamides as a new chemotype of 18 kDa translocator protein-selective ligand suitable for the development of positron emission tomography radioligands.Comparison of 18F- and 11C-labeled aryloxyanilide analogs to measure translocator protein in human brain using positron emission tomographyMixed-affinity binding in humans with 18-kDa translocator protein ligands.Evaluation of [(11)C]CB184 for imaging and quantification of TSPO overexpression in a rat model of herpes encephalitis.Kinetic analysis in healthy humans of a novel positron emission tomography radioligand to image the peripheral benzodiazepine receptor, a potential biomarker for inflammation.Microglial activation and progressive brain changes in schizophrenia.A Novel PET Imaging Probe for the Detection and Monitoring of Translocator Protein 18 kDa Expression in Pathological Disorders.Endotoxin-induced systemic inflammation activates microglia: [¹¹C]PBR28 positron emission tomography in nonhuman primatesIn vivo PET imaging of the neuroinflammatory response in rat spinal cord injury using the TSPO tracer [(18)F]GE-180 and effect of docosahexaenoic acidSingle-step high-yield radiosynthesis and evaluation of a sensitive 18F-labeled ligand for imaging brain peripheral benzodiazepine receptors with PET.Fully automated synthesis and initial PET evaluation of [11C]PBR28Stroke incidentally identified using improved positron emission tomography for microglial activationQuantification of translocator protein (18 kDa) in the human brain with PET and a novel radioligand, (18)F-PBR06.Application of microPET imaging approaches in the study of pediatric anesthetic-induced neuronal toxicity.Microglial depletion and activation: A [11C]PBR28 PET study in nonhuman primates.PET Imaging in Huntington's Disease.Brain translocator protein occupancy by ONO-2952 in healthy adults: A Phase 1 PET study using [11 C]PBR28.Considerations in the Development of Reversibly Binding PET Radioligands for Brain Imaging.The translocator protein ligand [¹⁸F]DPA-714 images glioma and activated microglia in vivo.In vivo (R)-[(11)C]PK11195 PET imaging of 18kDa translocator protein in recent onset psychosis.Test-retest reproducibility of [(11)C]PBR28 binding to TSPO in healthy control subjects.Assessing brain immune activation in psychiatric disorders: clinical and preclinical PET imaging studies of the 18-kDa translocator protein.[11C]PBR28 PET imaging is sensitive to neuroinflammation in the aged rat.Effect of stress and peripheral immune activation on astrocyte activation in transgenic bioluminescent Gfap-luc mice.PET imaging of putative microglial activation in individuals at ultra-high risk for psychosis, recently diagnosed and chronically ill with schizophrenia.Improved Automated Radiosynthesis of [(11)C]PBR28.The development of an automated and GMP compliant FASTlab™ Synthesis of [(18) F]GE-180; a radiotracer for imaging translocator protein (TSPO).Comparison of four 11C-labeled PET ligands to quantify translocator protein 18 kDa (TSPO) in human brain: (R)-PK11195, PBR28, DPA-713, and ER176-based on recent publications that measured specific-to-non-displaceable ratios.Recent Progress in the Development of TSPO PET Ligands for Neuroinflammation Imaging in Neurological Diseases.
P2860
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P2860
Brain and whole-body imaging in nonhuman primates of [11C]PBR28, a promising PET radioligand for peripheral benzodiazepine receptors
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
2007年论文
@zh
2007年论文
@zh-cn
name
Brain and whole-body imaging i ...... heral benzodiazepine receptors
@ast
Brain and whole-body imaging i ...... heral benzodiazepine receptors
@en
type
label
Brain and whole-body imaging i ...... heral benzodiazepine receptors
@ast
Brain and whole-body imaging i ...... heral benzodiazepine receptors
@en
prefLabel
Brain and whole-body imaging i ...... heral benzodiazepine receptors
@ast
Brain and whole-body imaging i ...... heral benzodiazepine receptors
@en
P2093
P2860
P1433
P1476
Brain and whole-body imaging i ...... heral benzodiazepine receptors
@en
P2093
Emmanuelle Briard
Jinsoo Hong
Jonathan P Gourley
Masahiro Fujita
Masao Imaizumi
Robert B Innis
Sami S Zoghbi
Victor W Pike
Yota Fujimura
P2860
P304
P356
10.1016/J.NEUROIMAGE.2007.09.063
P407
P577
2007-10-12T00:00:00Z