AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases - Wikidata - awgldk - TriplyDB

AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases

AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases

http://www.wikidata.org/entity/Q36513501

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Proximal nephron Actin cytoskeleton-dependent Rab GTPase-regulated angiotensin type I receptor lysosomal degradation studied by fluorescence lifetime imaging microscopy Transgenic mice expressing an intracellular fluorescent fusion of angiotensin II demonstrate renal thrombotic microangiopathy and elevated blood pressure.Mechanisms of AT1a receptor-mediated uptake of angiotensin II by proximal tubule cells: a novel role of the multiligand endocytic receptor megalin.Role of caveolin 1 in AT1a receptor-mediated uptake of angiotensin II in the proximal tubule of the kidney.Renin-angiotensin system in the kidney: What is new?New insights and perspectives on intrarenal renin-angiotensin system: focus on intracrine/intracellular angiotensin II Phosphoproteomic analysis of AT1 receptor-mediated signaling responses in proximal tubules of angiotensin II-induced hypertensive rats.Urinary Angiotensinogen as a Potential Biomarker of Intrarenal Renin-angiotensin System Activity in Chinese Patients with Chronic Kidney Disease.Novel signaling mechanisms of intracellular angiotensin II-induced NHE3 expression and activation in mouse proximal tubule cells.Cross-talk between angiotensin II and glucagon receptor signaling mediates phosphorylation of mitogen-activated protein kinases ERK 1/2 in rat glomerular mesangial cells.Effects of AT1 receptor-mediated endocytosis of extracellular Ang II on activation of nuclear factor-kappa B in proximal tubule cells Novel roles of intracrine angiotensin II and signalling mechanisms in kidney cells.Selective knockdown of AT1 receptors by RNA interference inhibits Val5-ANG II endocytosis and NHE-3 expression in immortalized rabbit proximal tubule cells.Genetic deletion of AT1a receptors attenuates intracellular accumulation of ANG II in the kidney of AT1a receptor-deficient mice.In vivo regulation of AT1a receptor-mediated intracellular uptake of [125I]Val5-ANG II in the kidneys and adrenals of AT1a receptor-deficient mice.Intracellular ANG II directly induces in vitro transcription of TGF-beta1, MCP-1, and NHE-3 mRNAs in isolated rat renal cortical nuclei via activation of nuclear AT1a receptors.Redox control of renal function and hypertension.Renin-angiotensin-aldosterone system-mediated redox effects in chronic kidney disease Augmentation of endogenous intrarenal angiotensin II levels in Val5-ANG II-infused rats.New frontiers in the intrarenal Renin-Angiotensin system: a critical review of classical and new paradigms.Evidence for a functional intracellular angiotensin system in the proximal tubule of the kidney.Angiotensin II-induced hypertension regulates AT1 receptor subtypes and extracellular matrix turnover in mouse retinal pigment epithelium Decreased renal perfusion rapidly increases plasma membrane Na-K-ATPase in rat cortex by an angiotensin II-dependent mechanism.AT1 receptor-mediated uptake of angiotensin II and NHE-3 expression in proximal tubule cells through a microtubule-dependent endocytic pathway.Angiotensin II counteracts the effects of cAMP/PKA on NHE3 activity and phosphorylation in proximal tubule cells.Recent Updates on the Proximal Tubule Renin-Angiotensin System in Angiotensin II-Dependent Hypertension.Physiology and Pathophysiology of the Intrarenal Renin-Angiotensin System: An Update.Potential therapeutic implications of intracrine angiogenesis.Nebivolol attenuates maladaptive proximal tubule remodeling in transgenic rats.Angiotensin II activation of mTOR results in tubulointerstitial fibrosis through loss of N-cadherin.Intracrine renin and angiotensin II: a novel role in cardiovascular and renal cellular regulation.Urinary angiotensinogen as a potential biomarker of intrarenal renin-angiotensin system activity in Chinese chronic kidney disease patients.

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AT1 receptor-mediated accumulation of extracellular angiotensin II in proximal tubule cells: role of cytoskeleton microtubules and tyrosine phosphatases

http://www.wikidata.org/entity/Q36513501

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American Journal of Physiology - Renal Physiology

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AT1 receptor-mediated accumula ...... ules and tyrosine phosphatases

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Jia L Zhuo

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L Gabriel Navar

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Oscar A Carretero

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Xiao C Li

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P2860

A role for a wortmannin-sensitive phosphatidylinositol-4-kinase in the endocytosis of muscarinic cholinergic receptors

Role of clathrin-mediated endocytosis in agonist-induced down-regulation of the beta2-adrenergic receptor

International union of pharmacology. XXIII. The angiotensin II receptors

Selective silencing of angiotensin receptor subtype 1a (AT1aR) by RNA interference

Internalization and trafficking of the human and rat growth hormone-releasing hormone receptor

Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling

Renal interstitial fluid angiotensin. Modulation by anesthesia, epinephrine, sodium depletion, and renin inhibition.

Receptor binding and internalization of a unique biologically active angiotensin II-colloidal gold conjugate: morphological analysis of angiotensin II processing in isolated vascular strips.

Endocytosis of membrane receptors: two pathways are better than one.

Endocytic traffic in polarized epithelial cells: role of the actin and microtubule cytoskeleton.

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