Lipid imbalance in the neurological disorder, Niemann-Pick C disease.
about
The pathogenesis of Niemann-Pick type C disease: a role for autophagy?Lipid rafts, cholesterol, and the brainNPC1/NPC2 function as a tag team duo to mobilize cholesterolCholesterol balance in prion diseases and Alzheimer's diseaseSusceptibility of outer hair cells to cholesterol chelator 2-hydroxypropyl-β-cyclodextrine is prestin-dependentMetals and cholesterol: two sides of the same coin in Alzheimer's disease pathology.Induced pluripotent stem cell models of lysosomal storage disorders.HFE gene variants, iron, and lipids: a novel connection in Alzheimer's diseaseSmith-Lemli-Opitz syndrome and inborn errors of cholesterol synthesis: summary of the 2007 SLO/RSH Foundation scientific conference sponsored by the National Institutes of Health.Altered levels and distribution of amyloid precursor protein and its processing enzymes in Niemann-Pick type C1-deficient mouse brainsMicroRNAs: a connection between cholesterol metabolism and neurodegeneration.Developmental ethanol exposure leads to dysregulation of lipid metabolism and oxidative stress in DrosophilaModulation of PICALM Levels Perturbs Cellular Cholesterol Homeostasis.Neuronal loss of Drosophila NPC1a causes cholesterol aggregation and age-progressive neurodegeneration.Cholesterol accumulation is associated with lysosomal dysfunction and autophagic stress in Npc1 -/- mouse brainInhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells.Endolysosome involvement in LDL cholesterol-induced Alzheimer's disease-like pathology in primary cultured neurons.In vivo antisense oligonucleotide reduction of NPC1 expression as a novel mouse model for Niemann Pick type C- associated liver disease.Diabetic larvae and obese flies-emerging studies of metabolism in Drosophila.Role of Endolysosomes in Skeletal Muscle Pathology Observed in a Cholesterol-Fed Rabbit Model of Alzheimer's Disease.Role of Lipids in Brain Injury and Diseases.Drosophila melanogaster as a model organism of brain diseasesFunctional interactions between sphingolipids and sterols in biological membranes regulating cell physiologyIntracellular sterol dynamicsAltered lipid metabolism in brain injury and disorders.Role for LAMP-2 in endosomal cholesterol transport.Regulation of fibroblast mitochondrial 27-hydroxycholesterol production by active plasma membrane cholesterol.Discovering novel brain lipids by liquid chromatography/tandem mass spectrometry.Cholesterol in Niemann-Pick Type C disease.Invertebrate models of lysosomal storage disease: what have we learned so far?Endocytosis and signaling: cell logistics shape the eukaryotic cell plan.Reciprocal regulation of cholesterol and beta amyloid at the subcellular level in Alzheimer's disease.Neuronopathic lysosomal storage diseases: clinical and pathologic findings.Role of endolysosomes and cholesterol in the pathogenesis of Alzheimer's disease: Insights into why statins might not provide clinical benefit.Modeling Niemann Pick type C1 using human embryonic and induced pluripotent stem cells.Cholesterol as a modifying agent of the neurovascular unit structure and function under physiological and pathological conditions.Impaired dynamics of the late endosome/lysosome compartment in human Niemann-Pick type C skin fibroblasts carrying mutation in NPC1 gene.Detergent-free isolation and characterization of cholesterol-rich membrane domains from trans-Golgi network vesicles.Cholesterol efflux via HDL resecretion occurs when cholesterol transport out of the lysosome is impaired.Increased activity and altered subcellular distribution of lysosomal enzymes determine neuronal vulnerability in Niemann-Pick type C1-deficient mice.
P2860
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P2860
Lipid imbalance in the neurological disorder, Niemann-Pick C disease.
description
2006 nî lūn-bûn
@nan
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
2006年论文
@zh
2006年论文
@zh-cn
name
Lipid imbalance in the neurological disorder, Niemann-Pick C disease.
@ast
Lipid imbalance in the neurological disorder, Niemann-Pick C disease.
@en
type
label
Lipid imbalance in the neurological disorder, Niemann-Pick C disease.
@ast
Lipid imbalance in the neurological disorder, Niemann-Pick C disease.
@en
prefLabel
Lipid imbalance in the neurological disorder, Niemann-Pick C disease.
@ast
Lipid imbalance in the neurological disorder, Niemann-Pick C disease.
@en
P2860
P1433
P1476
Lipid imbalance in the neurological disorder, Niemann-Pick C disease.
@en
P2093
Jean E Vance
P2860
P304
P356
10.1016/J.FEBSLET.2006.06.008
P407
P577
2006-06-15T00:00:00Z