Immunolocalization of Kex2 protease identifies a putative late Golgi compartment in the yeast Saccharomyces cerevisiae.
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The yeast RER2 gene, identified by endoplasmic reticulum protein localization mutations, encodes cis-prenyltransferase, a key enzyme in dolichol synthesisTwo GTPase isoforms, Ypt31p and Ypt32p, are essential for Golgi function in yeastStructural and enzymatic characterization of a purified prohormone-processing enzyme: secreted, soluble Kex2 proteaseTwo independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furinDistinct domains within Vps35p mediate the retrieval of two different cargo proteins from the yeast prevacuolar/endosomal compartmentSorting of yeast membrane proteins into an endosome-to-Golgi pathway involves direct interaction of their cytosolic domains with Vps35pTwo new Ypt GTPases are required for exit from the yeast trans-Golgi compartmentGene recruitment of the activated INO1 locus to the nuclear membranePeriplasmic Bar1 protease of Saccharomyces cerevisiae is active before reaching its extracellular destination.Targeting of chitin synthase 3 to polarized growth sites in yeast requires Chs5p and Myo2p.A screen for spore wall permeability mutants identifies a secreted protease required for proper spore wall assembly.The Saccharomyces cerevisiae MVP1 gene interacts with VPS1 and is required for vacuolar protein sorting.Yeast Vps55p, a functional homolog of human obesity receptor gene-related protein, is involved in late endosome to vacuole trafficking.Characterization of the yeast (1-->6)-beta-glucan biosynthetic components, Kre6p and Skn1p, and genetic interactions between the PKC1 pathway and extracellular matrix assembly.Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasisNovel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component.The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants.Allele-specific suppression of a defective trans-Golgi network (TGN) localization signal in Kex2p identifies three genes involved in localization of TGN transmembrane proteins.Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit).Golgi structure correlates with transitional endoplasmic reticulum organization in Pichia pastoris and Saccharomyces cerevisiae.The yeast proprotein convertase encoded by YAP3 is a glycophosphatidylinositol-anchored protein that localizes to the plasma membrane.Sbe2p and sbe22p, two homologous Golgi proteins involved in yeast cell wall formation.Vps52p, Vps53p, and Vps54p form a novel multisubunit complex required for protein sorting at the yeast late GolgiTrans-Golgi network and endosome dynamics connect ceramide homeostasis with regulation of the unfolded protein response and TOR signaling in yeast.Shared functions in vivo of a glycosyl-phosphatidylinositol-linked aspartyl protease, Mkc7, and the proprotein processing protease Kex2 in yeast.Functional characterization of the YUR1, KTR1, and KTR2 genes as members of the yeast KRE2/MNT1 mannosyltransferase gene family.The exocyst is an effector for Sec4p, targeting secretory vesicles to sites of exocytosis.The newly identified yeast GRD genes are required for retention of late-Golgi membrane proteins.Yeast homologues of tomosyn and lethal giant larvae function in exocytosis and are associated with the plasma membrane SNARE, Sec9Golgi localization and functionally important domains in the NH2 and COOH terminus of the yeast CLC putative chloride channel Gef1p.GTP hydrolysis is not important for Ypt1 GTPase function in vesicular transport.The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution.Localization and targeting of the Saccharomyces cerevisiae Kre2p/Mnt1p alpha 1,2-mannosyltransferase to a medial-Golgi compartmentSec6, Sec8, and Sec15 are components of a multisubunit complex which localizes to small bud tips in Saccharomyces cerevisiae.The vesicle transport protein Vps33p is an ATP-binding protein that localizes to the cytosol in an energy-dependent manner.Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants.Identification of a developmentally regulated septin and involvement of the septins in spore formation in Saccharomyces cerevisiae.SAC1p is an integral membrane protein that influences the cellular requirement for phospholipid transfer protein function and inositol in yeast.Kei1: a novel subunit of inositolphosphorylceramide synthase, essential for its enzyme activity and Golgi localization.A yeast Golgi E-type ATPase with an unusual membrane topology.
P2860
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P2860
Immunolocalization of Kex2 protease identifies a putative late Golgi compartment in the yeast Saccharomyces cerevisiae.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Immunolocalization of Kex2 pro ...... east Saccharomyces cerevisiae.
@ast
Immunolocalization of Kex2 pro ...... east Saccharomyces cerevisiae.
@en
type
label
Immunolocalization of Kex2 pro ...... east Saccharomyces cerevisiae.
@ast
Immunolocalization of Kex2 pro ...... east Saccharomyces cerevisiae.
@en
prefLabel
Immunolocalization of Kex2 pro ...... east Saccharomyces cerevisiae.
@ast
Immunolocalization of Kex2 pro ...... east Saccharomyces cerevisiae.
@en
P2093
P2860
P356
P1476
Immunolocalization of Kex2 pro ...... east Saccharomyces cerevisiae.
@en
P2093
P2860
P304
P356
10.1083/JCB.113.3.527
P407
P577
1991-05-01T00:00:00Z