Mechanism of the interaction of human platelet profilin with actin.
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The essential role of profilin in the assembly of actin for microspike formation.p140mDia, a mammalian homolog of Drosophila diaphanous, is a target protein for Rho small GTPase and is a ligand for profilin.Distinct biochemical characteristics of the two human profilin isoformsThe proline-rich focal adhesion and microfilament protein VASP is a ligand for profilinsActin dynamics in plateletsThe control of actin nucleotide exchange by thymosin beta 4 and profilin. A potential regulatory mechanism for actin polymerization in cellsPurification of a cortical complex containing two unconventional actins from Acanthamoeba by affinity chromatography on profilin-agaroseUnravelling the Actin Cytoskeleton: A New Competitive Edge?Dynamic reorganization of the actin cytoskeletonProfilin-1 serves as a gatekeeper for actin assembly by Arp2/3-dependent and -independent pathways.Modulation of actin structure and function by phosphorylation of Tyr-53 and profilin binding.Crystal Structures of Monomeric Actin Bound to Cytochalasin DThree-dimensional solution structure of Acanthamoeba profilin-IHigh rates of actin filament turnover in budding yeast and roles for actin in establishment and maintenance of cell polarity revealed using the actin inhibitor latrunculin-A.Mutational analysis of yeast profilin.Regulation of profilin localization in Saccharomyces cerevisiae by phosphoinositide metabolism.Yeast Arf3p modulates plasma membrane PtdIns(4,5)P2 levels to facilitate endocytosis.In vivo importance of actin nucleotide exchange catalyzed by profilin.Profilin is required for sustaining efficient intra- and intercellular spreading of Shigella flexneriInteraction of the Coxsackie and adenovirus receptor (CAR) with the cytoskeleton: binding to actinInteractions with PIP2, ADP-actin monomers, and capping protein regulate the activity and localization of yeast twinfilinControl of the ability of profilin to bind and facilitate nucleotide exchange from G-actin.Modeling capping protein FRAP and CALI experiments reveals in vivo regulation of actin dynamics.A central role for the WH2 domain of Srv2/CAP in recharging actin monomers to drive actin turnover in vitro and in vivo.The effects of ADF/cofilin and profilin on the conformation of the ATP-binding cleft of monomeric actinATP-dependent regulation of actin monomer-filament equilibrium by cyclase-associated protein and ADF/cofilinCharacterization and localization of profilin in pollen grains and tubes of Lilium longiflorum.Cofilin, actin and their complex observed in vivo using fluorescence resonance energy transfer.The open nucleotide pocket of the profilin/actin x-ray structure is unstable and closes in the absence of profilinPurification of actin from fission yeast Schizosaccharomyces pombe and characterization of functional differences from muscle actin.Actin and endocytosis in budding yeast.Dynamic actin structures stabilized by profilin.Regulation of growth cone actin dynamics by ADF/cofilin.Arrest of Listeria movement in host cells by a bacterial ActA analogue: implications for actin-based motility.Profilin binding to poly-L-proline and actin monomers along with ability to catalyze actin nucleotide exchange is required for viability of fission yeast.Compare and contrast actin filaments and microtubules.Mutant profilin suppresses mutant actin-dependent mitochondrial phenotype in Saccharomyces cerevisiae.Focusing on unpolymerized actinRecognition of two classes of oligoproline sequences in profilin-mediated acceleration of actin-based Shigella motility.The yeast V159N actin mutant reveals roles for actin dynamics in vivo.
P2860
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P2860
Mechanism of the interaction of human platelet profilin with actin.
description
1991 nî lūn-bûn
@nan
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
1991年论文
@zh
1991年论文
@zh-cn
name
Mechanism of the interaction of human platelet profilin with actin.
@ast
Mechanism of the interaction of human platelet profilin with actin.
@en
type
label
Mechanism of the interaction of human platelet profilin with actin.
@ast
Mechanism of the interaction of human platelet profilin with actin.
@en
prefLabel
Mechanism of the interaction of human platelet profilin with actin.
@ast
Mechanism of the interaction of human platelet profilin with actin.
@en
P2093
P2860
P356
P1476
Mechanism of the interaction of human platelet profilin with actin.
@en
P2093
L M Machesky
P J Goldschmidt-Clermont
S K Doberstein
P2860
P304
P356
10.1083/JCB.113.5.1081
P407
P577
1991-06-01T00:00:00Z