Mitochondrial calcium and reactive oxygen species regulate agonist-initiated platelet phosphatidylserine exposure
about
Platelet bioenergetic screen in sickle cell patients reveals mitochondrial complex V inhibition, which contributes to platelet activation.Targeting GPVI as a novel antithrombotic strategy.Redox Proteomics and Platelet Activation: Understanding the Redox Proteome to Improve Platelet Quality for TransfusionMitochondrially mediated integrin αIIbβ3 protein inactivation limits thrombus growth.KB-R7943, a plasma membrane Na(+)/Ca(2+) exchanger inhibitor, blocks opening of the mitochondrial permeability transition pore.Farnesoid X Receptor and Liver X Receptor Ligands Initiate Formation of Coated PlateletsThe role of mitochondrial permeability transition pore in regulating the shedding of the platelet GPIbα ectodomain.Auranofin, a thioredoxin reductase inhibitor, causes platelet death through calcium overload.Platelet subpopulations remain despite strong dual agonist stimulation and can be characterised using a novel six-colour flow cytometry protocol.Dynamics of calcium spiking, mitochondrial collapse and phosphatidylserine exposure in platelet subpopulations during activation.Systems biology insights into the meaning of the platelet's dual-receptor thrombin signaling.Inner Mitochondrial Membrane Disruption Links Apoptotic and Agonist-Initiated Phosphatidylserine Externalization in Platelets.Functional cyclophilin D moderates platelet adhesion, but enhances the lytic resistance of fibrin.Platelet Signaling Pathways and New Inhibitors.IL-17 Induces MPTP opening through ERK2 and P53 signaling pathway in human platelets.Loss of the mitochondrial kinase PINK1 does not alter platelet function
P2860
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P2860
Mitochondrial calcium and reactive oxygen species regulate agonist-initiated platelet phosphatidylserine exposure
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Mitochondrial calcium and reac ...... et phosphatidylserine exposure
@ast
Mitochondrial calcium and reac ...... et phosphatidylserine exposure
@en
type
label
Mitochondrial calcium and reac ...... et phosphatidylserine exposure
@ast
Mitochondrial calcium and reac ...... et phosphatidylserine exposure
@en
prefLabel
Mitochondrial calcium and reac ...... et phosphatidylserine exposure
@ast
Mitochondrial calcium and reac ...... et phosphatidylserine exposure
@en
P2093
P2860
P1476
Mitochondrial calcium and reac ...... et phosphatidylserine exposure
@en
P2093
Hyo-Jung Choo
Laura Mkumba
Mary B Wagner
Shawn M Jobe
Talib B Saafir
P2860
P304
P356
10.1161/ATVBAHA.112.300433
P407
P577
2012-10-18T00:00:00Z