HIV recombination: what is the impact on antiretroviral therapy?
about
Increased burst size in multiply infected cells can alter basic virus dynamicsViral quasispecies evolutionEmergence of recombinant forms of HIV: dynamics and scalingAccurately measuring recombination between closely related HIV-1 genomesTiming the emergence of resistance to anti-HIV drugs with large genetic barriersStochastic simulations suggest that HIV-1 survives close to its error thresholdRecombination accelerates adaptation on a large-scale empirical fitness landscape in HIV-1Synaptic transmission and the susceptibility of HIV infection to anti-viral drugsModeling and estimation of kinetic parameters and replicative fitness of HIV-1 from flow-cytometry-based growth competition experiments.Taking multiple infections of cells and recombination into account leads to small within-host effective-population-size estimates of HIV-1The role of recombination for the coevolutionary dynamics of HIV and the immune responseCirculating virus load determines the size of bottlenecks in viral populations progressing within a host.Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort.Genetic Consequences of Antiviral Therapy on HIV-1.The Role of Recombination in Evolutionary Rescue.Clonality and intracellular polyploidy in virus evolution and pathogenesisRecombination favors the evolution of drug resistance in HIV-1 during antiretroviral therapy.Modeling sequence evolution in HIV-1 infection with recombinationA phylogenetic and Markov model approach for the reconstruction of mutational pathways of drug resistance.Effect of multiple infection of cells on the evolutionary dynamics of HIV in vivo: implications for host adaptation mechanisms.Suboptimal provirus expression explains apparent nonrandom cell coinfection with HIV-1.Modeling multiple infection of cells by viruses: Challenges and insights.Accelerated crossing of fitness valleys through division of labor and cheating in asexual populations.Effect of different modes of viral spread on the dynamics of multiply infected cells in human immunodeficiency virus infection.Virus dynamics in the presence of synaptic transmissionThe evolutionary epidemiology of multilocus drug resistance.Impaired immune evasion in HIV through intracellular delays and multiple infection of cells.Sanger and Next Generation Sequencing Approaches to Evaluate HIV-1 Virus in Blood Compartments
P2860
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P2860
HIV recombination: what is the impact on antiretroviral therapy?
description
2005 nî lūn-bûn
@nan
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
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2005年论文
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2005年论文
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name
HIV recombination: what is the impact on antiretroviral therapy?
@ast
HIV recombination: what is the impact on antiretroviral therapy?
@en
type
label
HIV recombination: what is the impact on antiretroviral therapy?
@ast
HIV recombination: what is the impact on antiretroviral therapy?
@en
prefLabel
HIV recombination: what is the impact on antiretroviral therapy?
@ast
HIV recombination: what is the impact on antiretroviral therapy?
@en
P2860
P356
P1476
HIV recombination: what is the impact on antiretroviral therapy?
@en
P2860
P304
P356
10.1098/RSIF.2005.0064
P577
2005-12-01T00:00:00Z