Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition.
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Mutational Strand Asymmetries in Cancer Genomes Reveal Mechanisms of DNA Damage and Repair.The Role of the Core Non-Homologous End Joining Factors in Carcinogenesis and Cancer.Ovarian Cancers Harbor Defects in Nonhomologous End Joining Resulting in Resistance to Rucaparib.Targeting the ATR-CHK1 Axis in Cancer TherapyTherapeutic targeting of PGBD5-induced DNA repair dependency in pediatric solid tumors.Loss of NEIL3 DNA glycosylase markedly increases replication associated double strand breaks and enhances sensitivity to ATR inhibitor in glioblastoma cells.Synthetic lethality of PARP inhibitors in combination with MYC blockade is independent of BRCA status in triple negative breast cancer.Local DNA Repair Inhibition for Sustained Radiosensitization of High-Grade Gliomas.The ATR inhibitor AZD6738 synergizes with gemcitabine in vitro and in vivo to induce pancreatic ductal adenocarcinoma regression.The Impact of p53 Dysfunction in ATR Inhibitor Cytotoxicity and Chemo- and RadiosensitisationCharacterization and drug sensitivity of a novel human ovarian clear cell carcinoma cell line genomically and phenotypically similar to the original tumor
P2860
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P2860
Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Common cancer-associated imbal ...... o single agent ATR inhibition.
@ast
Common cancer-associated imbal ...... o single agent ATR inhibition.
@en
type
label
Common cancer-associated imbal ...... o single agent ATR inhibition.
@ast
Common cancer-associated imbal ...... o single agent ATR inhibition.
@en
prefLabel
Common cancer-associated imbal ...... o single agent ATR inhibition.
@ast
Common cancer-associated imbal ...... o single agent ATR inhibition.
@en
P2093
P2860
P50
P356
P1433
P1476
Common cancer-associated imbal ...... o single agent ATR inhibition.
@en
P2093
Aiste McCormick
Ashleigh Herriott
Claire J Elstob
Felicity E B May
Fiona K Middleton
James M Allan
John R Pollard
Miranda J Patterson
Sarah Fordham
P2860
P304
32396-32409
P356
10.18632/ONCOTARGET.6136
P407
P577
2015-10-01T00:00:00Z