Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression.

Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression.

Item
http://www.wikidata.org/entity/Q36545721
NT1014, a novel biguanide, inhibits ovarian cancer growth in vitro and in vivo.Dichloroacetate and metformin synergistically suppress the growth of ovarian cancer cells.Results from 11C-metformin-PET scans, tissue analysis and cellular drug-sensitivity assays questions the view that biguanides affects tumor respiration directly.Metformin is also effective on lactic acidosis-exposed melanoma cells switched to oxidative phosphorylation.Metabolic Flexibility in Health and Disease.Metabolic reprogramming in the tumour microenvironment: a hallmark shared by cancer cells and T lymphocytes.The Mitochondrial Complex(I)ty of Cancer.Combined Inhibitions of Glycolysis and AKT/autophagy Can Overcome Resistance to EGFR-targeted Therapy of Lung Cancer.Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications.Metabolic flexibility as an adaptation to energy resources and requirements in health and disease.The elevated glutaminolysis of bladder cancer and T cells in a simulated tumor microenvironment contributes to the up-regulation of PD-L1 expression by interferon-γMetabolic Profiles Associated With Metformin Efficacy in CancerMetabolic Targeting of Breast Cancer Cells With the 2-Deoxy-D-Glucose and the Mitochondrial Bioenergetics Inhibitor MDIVI-1Combined Modulation of Tumor Metabolism by Metformin and Diclofenac in Glioma
P2860

Targeting metabolic flexibility by simultaneously inhibiting respiratory complex I and lactate generation retards melanoma progression.

Item
http://www.wikidata.org/entity/Q36545721
description
2015 nî lūn-bûn
@nan
2015年の論文
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2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
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2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Targeting metabolic flexibilit ...... retards melanoma progression.
@ast
Targeting metabolic flexibilit ...... retards melanoma progression.
@en
type
label
Targeting metabolic flexibilit ...... retards melanoma progression.
@ast
Targeting metabolic flexibilit ...... retards melanoma progression.
@en
prefLabel
Targeting metabolic flexibilit ...... retards melanoma progression.
@ast
Targeting metabolic flexibilit ...... retards melanoma progression.
@en
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Targeting metabolic flexibilit ...... n retards melanoma progression
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P698
P932