Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival - Wikidata - awgldk - TriplyDB

Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival

Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival

http://www.wikidata.org/entity/Q36547694

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Cerebrospinal fluid peptides as potential Parkinson disease biomarkers: a staged pipeline for discovery and validation.Microglia protect against brain injury and their selective elimination dysregulates neuronal network activity after stroke.Network Topology Analysis of Post-Mortem Brain Microarrays Identifies More Alzheimer's Related Genes and MicroRNAs and Points to Novel Routes for Fighting with the Disease Induction of microglia activation after infection with the non-neurotropic A/CA/04/2009 H1N1 influenza virus.Preclinical Assessment of Young Blood Plasma for Alzheimer Disease.CSF-1 receptor signaling in myeloid cells Depletion of microglia exacerbates postischemic inflammation and brain injury Regulation of Embryonic and Postnatal Development by the CSF-1 Receptor.Colony stimulating factor 1 receptor inhibition eliminates microglia and attenuates brain injury after intracerebral hemorrhage.The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration.Glycoproteomic study reveals altered plasma proteins associated with HIV elite suppressors.Temporal gene profiling of the 5XFAD transgenic mouse model highlights the importance of microglial activation in Alzheimer's disease.CSF-1R inhibition alters macrophage polarization and blocks glioma progression.Phenotypic characterization of a Csf1r haploinsufficient mouse model of adult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP).Pleiotropic effects of extended blockade of CSF1R signaling in adult mice.Interleukin-34 restores blood-brain barrier integrity by upregulating tight junction proteins in endothelial cells.Characterisation of a novel Fc conjugate of macrophage colony-stimulating factor.Macrophage-Colony Stimulating Factor Derived from Injured Primary Afferent Induces Proliferation of Spinal Microglia and Neuropathic Pain in Rats.Receptor-Type Protein-Tyrosine Phosphatase ζ and Colony Stimulating Factor-1 Receptor in the Intestine: Cellular Expression and Cytokine- and Chemokine Responses by Interleukin-34 and Colony Stimulating Factor-1.TREM2 regulates microglial cell activation in response to demyelination in vivo.CSF1 Restores Innate Immunity After Liver Injury in Mice and Serum Levels Indicate Outcomes of Patients With Acute Liver Failure.Emerging Roles for CSF-1 Receptor and its Ligands in the Nervous System.Microglia regulate hippocampal neurogenesis during chronic neurodegeneration Transcriptional landscapes at the intersection of neuronal apoptosis and substance P-induced survival: exploring pathways and drug targets.Long-term cognitive impairments and pathological alterations in a mouse model of repetitive mild traumatic brain injury.Haploinsufficiency of CSF-1R and clinicopathologic characterization in patients with HDLS.Interkeukin-34, a cytokine crucial for the differentiation and maintenance of tissue resident macrophages and Langerhans cells.Genetic targeting of microglia.Role for cFMS in maintaining alternative macrophage polarization in SIV infection: implications for HIV neuropathogenesis.Help-me signaling: Non-cell autonomous mechanisms of neuroprotection and neurorecovery.Chronicity following ischaemia-reperfusion injury depends on tubular-macrophage crosstalk involving two tubular cell-derived CSF-1R activators: CSF-1 and IL-34.Biological role of granulocyte macrophage colony-stimulating factor (GM-CSF) and macrophage colony-stimulating factor (M-CSF) on cells of the myeloid lineage.CSF1R mutations in hereditary diffuse leukoencephalopathy with spheroids are loss of function.Immunoregulatory properties of the cytokine IL-34.Ontogeny and homeostasis of CNS myeloid cells.Therapeutic Strategies Under Development Targeting Inflammatory Mechanisms in Amyotrophic Lateral Sclerosis.Microglia in steady state.Deficiency in Neuronal TGF-β Signaling Leads to Nigrostriatal Degeneration and Activation of TGF-β Signaling Protects against MPTP Neurotoxicity in Mice.TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway.Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex.

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Colony-stimulating factor 1 receptor (CSF1R) signaling in injured neurons facilitates protection and survival

http://www.wikidata.org/entity/Q36547694

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2013 nî lūn-bûn

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Colony-stimulating factor 1 re ...... itates protection and survival

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Colony-stimulating factor 1 re ...... itates protection and survival

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Colony-stimulating factor 1 re ...... itates protection and survival

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Colony-stimulating factor 1 re ...... itates protection and survival

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Colony-stimulating factor 1 re ...... itates protection and survival

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Journal of Experimental Medicine

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Colony-stimulating factor 1 re ...... itates protection and survival

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Fiona Elwood

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Gordon Wong

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Haitham Alabsi

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Hui Zhang

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Jane Relton

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Jeffrey W Pollard

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Liyin Zhu

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Michelle L James

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Nina Fainberg

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Rafael Wabl

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Discovery of a cytokine and its receptor by functional screening of the extracellular proteome

Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells

Pathways towards and away from Alzheimer's disease

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1

The c-fms proto-oncogene product is related to the receptor for the mononuclear phagocyte growth factor, CSF-1

The CSF-1 receptor ligands IL-34 and CSF-1 exhibit distinct developmental brain expression patterns and regulate neural progenitor cell maintenance and maturation

The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice.

The molecular biology of memory storage: a dialogue between genes and synapses

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157-172

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10.1084/JEM.20120412

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1

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210

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Markus Britschgi

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2013-01-07T00:00:00Z

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234084602

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23296467

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3549715

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