Functional interaction of c-Ets-1 and GHF-1/Pit-1 mediates Ras activation of pituitary-specific gene expression: mapping of the essential c-Ets-1 domain.
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Sp100 interacts with ETS-1 and stimulates its transcriptional activityPit-1 and GATA-2 interact and functionally cooperate to activate the thyrotropin beta-subunit promoterCEBPD suppresses prolactin expression and prolactinoma cell proliferationA Pit-1 threonine 220 phosphomimic reduces binding to monomeric DNA sites to inhibit Ras and estrogen stimulation of the prolactin gene promoterRas-mediated phosphorylation of a conserved threonine residue enhances the transactivation activities of c-Ets1 and c-Ets2Selective inhibition of prolactin gene transcription by the ETS-2 repressor factor.Molecular interaction of BMP-4, TGF-beta, and estrogens in lactotrophs: impact on the PRL promoter.CArG binding factor A (CBF-A) is involved in transcriptional regulation of the rat Ha-ras promoter.Epstein-barr virus nuclear antigen 3C activates the latent membrane protein 1 promoter in the presence of Epstein-Barr virus nuclear antigen 2 through sequences encompassing an spi-1/Spi-B binding site.Control of B cell development by Ras-mediated activation of Raf.IL-2 and long-term T cell activation induce physical and functional interaction between STAT5 and ETS transcription factors in human T cells.Regulation of Ets function by protein - protein interactions.Ets target genes: past, present and future.A role for CREB binding protein and p300 transcriptional coactivators in Ets-1 transactivation functionsSignal transduction and the Ets family of transcription factors.Pituitary Ets-1 and GABP bind to the growth factor regulatory sites of the rat prolactin promoter.Epidermal growth factor and Ras regulate gene expression in GH4 pituitary cells by separate, antagonistic signal transduction pathways.Site-specific methylation of the rat prolactin and growth hormone promoters correlates with gene expressionInteraction of Ets-1 and the POU-homeodomain protein GHF-1/Pit-1 reconstitutes pituitary-specific gene expression.Methylation of an ETS site in the intron enhancer of the keratin 18 gene participates in tissue-specific repressionNet-b, a Ras-insensitive factor that forms ternary complexes with serum response factor on the serum response element of the fos promoterMolecular physiology of pituitary development: signaling and transcriptional networks.Ets-1 regulates radial glia formation during vertebrate embryogenesis.The 26-amino acid beta-motif of the Pit-1beta transcription factor is a dominant and independent repressor domainSelective constraints on the activation domain of transcription factor Pit-1.The kidney-expressed winged helix transcription factor FREAC-4 is regulated by Ets-1. A possible role in kidney development.Characterization of a novel protein kinase C response element in the glucagon gene.c-ETS1 facilitates G1/S-phase transition by up-regulating cyclin E and CDK2 genes and cooperates with hepatitis B virus X protein for their deregulationDifferentiation of lactotrope precursor GHFT cells in response to fibroblast growth factor-2.An activation function in Pit-1 required selectively for synergistic transcription.A composite Ets/Pit-1 binding site in the prolactin gene can mediate transcriptional responses to multiple signal transduction pathways.Ras signaling and transcriptional synergy at a flexible Ets-1/Pit-1 composite DNA element is defined by the assembly of selective activation domains.The Pit-1 homeodomain and beta-domain interact with Ets-1 and modulate synergistic activation of the rat prolactin promoter.The Pit-1beta domain dictates active repression and alteration of histone acetylation of the proximal prolactin promoter.Thyroid hormone receptor beta2 promoter activity in pituitary cells is regulated by Pit-1.A 26-amino acid insertion domain defines a functional transcription switch motif in Pit-1beta.The possible functions of duplicated ets (GGAA) motifs located near transcription start sites of various human genesFunctional components of fibroblast growth factor (FGF) signal transduction in pituitary cells. Identification of FGF response elements in the prolactin gene.GHF-1/Pit-1 functions as a cell-specific integrator of Ras signaling by targeting the Ras pathway to a composite Ets-1/GHF-1 response element.
P2860
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P2860
Functional interaction of c-Ets-1 and GHF-1/Pit-1 mediates Ras activation of pituitary-specific gene expression: mapping of the essential c-Ets-1 domain.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Functional interaction of c-Et ...... the essential c-Ets-1 domain.
@ast
Functional interaction of c-Et ...... the essential c-Ets-1 domain.
@en
type
label
Functional interaction of c-Et ...... the essential c-Ets-1 domain.
@ast
Functional interaction of c-Et ...... the essential c-Ets-1 domain.
@en
prefLabel
Functional interaction of c-Et ...... the essential c-Ets-1 domain.
@ast
Functional interaction of c-Et ...... the essential c-Ets-1 domain.
@en
P2093
P2860
P356
P1476
Functional interaction of c-Et ...... the essential c-Ets-1 domain.
@en
P2093
A Gutierrez-Hartmann
A P Bradford
K E Conrad
P2860
P304
P356
10.1128/MCB.15.5.2849
P407
P577
1995-05-01T00:00:00Z