Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function.
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STAT5 in hematopoietic stem cell biology and transplantationMolecular Models of STAT5A Tetramers Complexed to DNA Predict Relative Genome-Wide Frequencies of the Spacing between the Two Dimer Binding Motifs of the Tetramer Binding SitesThe natural chemopreventive agent sulforaphane inhibits STAT5 activityHow Intrinsic Molecular Dynamics Control Intramolecular Communication in Signal Transducers and Activators of Transcription Factor STAT5BATF-JUN is critical for IRF4-mediated transcription in T cellsBioinformatic screening of autoimmune disease genes and protein structure prediction with FAMS for drug discoveryEssential biphasic role for JAK3 catalytic activity in IL-2 receptor signalingCD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesisPhosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complexSignal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8+ T cells by preventing terminal effector differentiation.Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation.Transcriptional control of effector and memory CD8+ T cell differentiation.Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation.Stat5 signaling specifies basal versus stress erythropoietic responses through distinct binary and graded dynamic modalities.DNA methylation and transcription in a distal region upstream from the bovine AlphaS1 casein gene after once or twice daily milking.Comprehensive meta-analysis of Signal Transducers and Activators of Transcription (STAT) genomic binding patterns discerns cell-specific cis-regulatory modulesEGR2 is critical for peripheral naïve T-cell differentiation and the T-cell response to influenza.Genome wide mapping reveals PDE4B as an IL-2 induced STAT5 target gene in activated human PBMCs and lymphoid cancer cellsFRA2 is a STAT5 target gene regulated by IL-2 in human CD4 T cells.The synthetic α-bromo-2',3,4,4'-tetramethoxychalcone (α-Br-TMC) inhibits the JAK/STAT signaling pathway.Interleukin-7 optimizes FOXP3+CD4+ regulatory T cells reactivity to interleukin-2 by modulating CD25 expression.Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+ T cellsMechanisms of Jak/STAT signaling in immunity and diseaseImpact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional ActivityTIGERi: modeling and visualizing the responses to perturbation of a transcription factor network.Common gamma chain cytokines in combinatorial immune strategies against cancerContext and location dependence of adaptive Foxp3(+) regulatory T cell formation during immunopathological conditionsSequential activation of genetic programs in mouse mammary epithelium during pregnancy depends on STAT5A/B concentration.An autoregulatory enhancer controls mammary-specific STAT5 functions.Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapyDifferential regulation of hepatic organic cation transporter 1, organic anion-transporting polypeptide 1a4, bile-salt export pump, and multidrug resistance-associated protein 2 transporter expression in lymphocyte-deficient mice associates with intSTAT5 polarization promotes iTregs and suppresses human T-cell alloresponses while preserving CTL capacity.STAT5-induced lunatic fringe during Th2 development alters delta-like 4-mediated Th2 cytokine production in respiratory syncytial virus-exacerbated airway allergic diseaseThe serum protein profile of early parity which induces protection against breast cancer.STAT heterodimers in immunity: A mixed message or a unique signal?Genomic and computational approaches to dissect the mechanisms of STAT3's universal and cell type-specific functions.STAT5 acetylation: Mechanisms and consequences for immunological control and leukemogenesis.Direct targets of pSTAT5 signalling in erythropoiesis.A myeloid tumor suppressor role for NOL3Three Tyrosine Residues in the Erythropoietin Receptor Are Essential for Janus Kinase 2 V617F Mutant-induced Tumorigenesis.
P2860
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P2860
Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function.
description
2012 nî lūn-bûn
@nan
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
2012年论文
@zh
2012年论文
@zh-cn
name
Critical Role of STAT5 transcr ...... es and normal immune function.
@ast
Critical Role of STAT5 transcr ...... es and normal immune function.
@en
type
label
Critical Role of STAT5 transcr ...... es and normal immune function.
@ast
Critical Role of STAT5 transcr ...... es and normal immune function.
@en
prefLabel
Critical Role of STAT5 transcr ...... es and normal immune function.
@ast
Critical Role of STAT5 transcr ...... es and normal immune function.
@en
P2093
P2860
P1433
P1476
Critical Role of STAT5 transcr ...... es and normal immune function.
@en
P2093
Brian L Kelsall
Chengyu Liu
Delong Liu
Hyun Tak Jin
Jian-Xin Lin
Jianping He
Kairong Cui
Mohammed Ata Ur Rasheed
P2860
P304
P356
10.1016/J.IMMUNI.2012.02.017
P407
P577
2012-04-01T00:00:00Z