Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function. - Wikidata - awgldk - TriplyDB

Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function.

Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function.

http://www.wikidata.org/entity/Q36551220

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STAT5 in hematopoietic stem cell biology and transplantation Molecular Models of STAT5A Tetramers Complexed to DNA Predict Relative Genome-Wide Frequencies of the Spacing between the Two Dimer Binding Motifs of the Tetramer Binding Sites The natural chemopreventive agent sulforaphane inhibits STAT5 activity How Intrinsic Molecular Dynamics Control Intramolecular Communication in Signal Transducers and Activators of Transcription Factor STAT5 BATF-JUN is critical for IRF4-mediated transcription in T cells Bioinformatic screening of autoimmune disease genes and protein structure prediction with FAMS for drug discovery Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling CD8(+) T-cell effector function and transcriptional regulation during HIV pathogenesis Phosphorylated STAT5 directly facilitates parvovirus B19 DNA replication in human erythroid progenitors through interaction with the MCM complex Signal-transducing adaptor protein-2 promotes generation of functional long-term memory CD8+ T cells by preventing terminal effector differentiation.Benzotriazoles Reactivate Latent HIV-1 through Inactivation of STAT5 SUMOylation.Transcriptional control of effector and memory CD8+ T cell differentiation.Alternative ways of modulating JAK-STAT pathway: Looking beyond phosphorylation.Stat5 signaling specifies basal versus stress erythropoietic responses through distinct binary and graded dynamic modalities.DNA methylation and transcription in a distal region upstream from the bovine AlphaS1 casein gene after once or twice daily milking.Comprehensive meta-analysis of Signal Transducers and Activators of Transcription (STAT) genomic binding patterns discerns cell-specific cis-regulatory modules EGR2 is critical for peripheral naïve T-cell differentiation and the T-cell response to influenza.Genome wide mapping reveals PDE4B as an IL-2 induced STAT5 target gene in activated human PBMCs and lymphoid cancer cells FRA2 is a STAT5 target gene regulated by IL-2 in human CD4 T cells.The synthetic α-bromo-2',3,4,4'-tetramethoxychalcone (α-Br-TMC) inhibits the JAK/STAT signaling pathway.Interleukin-7 optimizes FOXP3+CD4+ regulatory T cells reactivity to interleukin-2 by modulating CD25 expression.Opposing roles of STAT1 and STAT3 in IL-21 function in CD4+ T cells Mechanisms of Jak/STAT signaling in immunity and disease Impact of the N-Terminal Domain of STAT3 in STAT3-Dependent Transcriptional Activity TIGERi: modeling and visualizing the responses to perturbation of a transcription factor network.Common gamma chain cytokines in combinatorial immune strategies against cancer Context and location dependence of adaptive Foxp3(+) regulatory T cell formation during immunopathological conditions Sequential activation of genetic programs in mouse mammary epithelium during pregnancy depends on STAT5A/B concentration.An autoregulatory enhancer controls mammary-specific STAT5 functions.Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy Differential regulation of hepatic organic cation transporter 1, organic anion-transporting polypeptide 1a4, bile-salt export pump, and multidrug resistance-associated protein 2 transporter expression in lymphocyte-deficient mice associates with int STAT5 polarization promotes iTregs and suppresses human T-cell alloresponses while preserving CTL capacity.STAT5-induced lunatic fringe during Th2 development alters delta-like 4-mediated Th2 cytokine production in respiratory syncytial virus-exacerbated airway allergic disease The serum protein profile of early parity which induces protection against breast cancer.STAT heterodimers in immunity: A mixed message or a unique signal?Genomic and computational approaches to dissect the mechanisms of STAT3's universal and cell type-specific functions.STAT5 acetylation: Mechanisms and consequences for immunological control and leukemogenesis.Direct targets of pSTAT5 signalling in erythropoiesis.A myeloid tumor suppressor role for NOL3 Three Tyrosine Residues in the Erythropoietin Receptor Are Essential for Janus Kinase 2 V617F Mutant-induced Tumorigenesis.

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Critical Role of STAT5 transcription factor tetramerization for cytokine responses and normal immune function.

http://www.wikidata.org/entity/Q36551220

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Critical Role of STAT5 transcr ...... es and normal immune function.

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Critical Role of STAT5 transcr ...... es and normal immune function.

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J.IMMUNI.2012.02.017

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Critical Role of STAT5 transcr ...... es and normal immune function.

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Brian L Kelsall

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Chengyu Liu

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Delong Liu

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Hyun Tak Jin

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Jian-Xin Lin

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Jianping He

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Kairong Cui

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Lu Wang

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Mohammed Ata Ur Rasheed

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Peng Li

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Model-based analysis of ChIP-Seq (MACS)

Stat5 is required for IL-2-induced cell cycle progression of peripheral T cells

The human perforin gene is a direct target of STAT4 activated by IL-12 in NK cells

Cloning of human Stat5B. Reconstitution of interleukin-2-induced Stat5A and Stat5B DNA binding activity in COS-7 cells

Epigenetic repression of the Igk locus by STAT5-mediated recruitment of the histone methyltransferase Ezh2

Structure of the amino-terminal protein interaction domain of STAT-4

Fitting a mixture model by expectation maximization to discover motifs in biopolymers

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

Fetal anemia and apoptosis of red cell progenitors in Stat5a-/-5b-/- mice: a direct role for Stat5 in Bcl-X(L) induction

Restoring function in exhausted CD8 T cells during chronic viral infection

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586-599

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10.1016/J.IMMUNI.2012.02.017

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4

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36

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2012-04-01T00:00:00Z

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224812264

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22520852

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3551341

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