Distance from sub-Saharan Africa predicts mutational load in diverse human genomes.
about
Human Knockout Carriers: Dead, Diseased, Healthy, or Improved?Understanding rare and common diseases in the context of human evolutionFire Usage and Ancient Hominin Detoxification Genes: Protective Ancestral Variants Dominate While Additional Derived Risk Variants Appear in Modern HumansGenetics of Type 2 Diabetes: the Power of Isolated Populations.Rapid trait evolution drives increased speed and variance in experimental range expansionsInference of the Distribution of Selection Coefficients for New Nonsynonymous Mutations Using Large Samples.Prediction of harmful variants on mitochondrial genes: Test of habitat-dependent and demographic effects in a euryhaline fish.Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs.The Genetic Cost of Neanderthal Introgression.Small Traditional Human Communities Sustain Genomic Diversity over Microgeographic Scales despite Linguistic Isolation.Population genetic analysis of the DARC locus (Duffy) reveals adaptation from standing variation associated with malaria resistance in humans.Patterns of deleterious variation between human populations reveal an unbalanced load.Challenges and disparities in the application of personalized genomic medicine to populations with African ancestry.A continuum of admixture in the Western Hemisphere revealed by the African Diaspora genome.Modeling Human Population Separation History Using Physically Phased Genomes.A Temporal Perspective on the Interplay of Demography and Selection on Deleterious Variation in Humans.Cassava haplotype map highlights fixation of deleterious mutations during clonal propagation.Inferring Demographic History Using Two-Locus Statistics.Living in an adaptive world: Genomic dissection of the genus Homo and its immune response.The impact of recent population history on the deleterious mutation load in humans and close evolutionary relatives.Recombination Rate Variation, Hitchhiking, and Demographic History Shape Deleterious Load in Poplar.When Is Selection Effective?Accumulation of Deleterious Mutations During Bacterial Range Expansions.MtDNA genomes reveal a relaxation of selective constraints in low-BMI individuals in a Uyghur population.Slightly deleterious genomic variants and transcriptome perturbations in Down syndrome embryonic selection.Bioinformatically predicted deleterious mutations reveal complementation in the interior spruce hybrid complex.Genetic costs of domestication and improvement.Admixture on the northern front: population genomics of range expansion in the white-footed mouse (Peromyscus leucopus) and secondary contact with the deer mouse (Peromyscus maniculatus).The Effect of an Extreme and Prolonged Population Bottleneck on Patterns of Deleterious Variation: Insights from the Greenlandic Inuit.Whole-genome sequencing for an enhanced understanding of genetic variation among South Africans.Evolutionary genomics of grape (Vitis vinifera ssp. vinifera) domestication.An Unexpectedly Complex Architecture for Skin Pigmentation in Africans.Comparison of Single Genome and Allele Frequency Data Reveals Discordant Demographic Histories.PGG.Population: a database for understanding the genomic diversity and genetic ancestry of human populations.Demography and mating system shape the genome-wide impact of purifying selection in Arabis alpina.Dominant-negative loss of function arises from a second, more frequent variant within the SAND domain of autoimmune regulator (AIRE).Genetic variation in human drug-related genes.Elevated Proportions of Deleterious Genetic Variation in Domestic Animals and Plants.Comparative Genomics Approaches Accurately Predict Deleterious Variants in PlantsHaplotype Sharing Provides Insights into Fine-Scale Population History and Disease in Finland
P2860
Q26764736-CB0ED56C-F8F8-406A-B67E-3EC23DD752FDQ28067740-26C0A3D7-E539-4DD0-865E-539473126494Q28595433-C2226EB6-01FA-418A-8463-23350611E1A8Q30250281-830C7A39-E6AB-4EFB-993B-FC0FA9F15770Q31157299-ED599C27-4297-4C1C-90F6-0A73D5FAABE7Q33642802-34D57A4D-0D9F-42C5-A632-482744A8143EQ33789110-16FAFCC0-BABD-4B60-B34B-50BB1EDEE4D5Q34506401-1FF913E2-806E-4DA9-BF4F-DF54E03EE2F2Q35977651-1CFB10CD-27BA-4408-AF3F-65194CD78E56Q36044357-52DA8921-0B41-4953-A1F6-EFF30EA209FDQ36304173-F10C3219-582B-48A2-96A1-7ECEA139D19EQ36551540-18215020-DC11-43CD-8C38-E74E04E79EC8Q37336084-8F5BD251-BEAD-4B5F-9EF4-25CB24FD8846Q37336092-3BBBE2AA-A09A-4513-869E-DC65C6616CE1Q37576477-948BC288-265E-442A-A95C-BAF241C5119EQ37693465-E8F90FE8-87F4-4675-95CB-15DA713CB266Q38729280-9FC4B1A2-0FF5-42E8-B683-7A501C38C3E6Q38835112-2C5B7041-6574-49D6-8201-DF2A3AA93C92Q38870254-3831FAD4-1F6C-4808-AB55-7FA48D3D2715Q38981635-1D5B7316-7091-418E-B777-B25DA523DF9DQ39501443-3A140D39-B33A-40A4-91DF-698532D9B99FQ39892515-B9B1B763-22F6-4172-ABB7-C76EAD68D206Q42371063-8E058CC3-9754-45CD-9A8D-AE2DE9519C2AQ44038959-8BA003C2-FA3D-46E6-9F23-80CBBBA5ADE3Q46182550-1A6157A4-0981-4262-85D9-24E62FD5ADB1Q46238763-804707E5-3402-4084-8025-04D9012DF0A8Q46290705-CAB77895-57C2-4D99-8912-FF7352394703Q46307722-0128274F-B6D3-4FC8-90EA-77BBC29A50A8Q46545285-E1F1211B-F2CA-42A6-B6C0-F26D3BCBA3E7Q46588085-32C7BDB1-192B-4F38-85CB-D86BD46A4032Q46684466-362B418E-F4BB-423D-BF18-78E05EFFECAFQ46760865-88A52F6A-10A2-4773-A4A4-7796EED8D382Q46959041-CE801B70-510E-498B-9B09-FC2194893FF7Q47103266-F603860C-32E2-46BC-B44B-44DF5C5B0B49Q47208085-359607BD-3C77-4749-A2AD-91DA93947B3AQ47412103-FD682922-8C2B-44AA-AFED-BF2B6D78A36FQ47564586-A7B5E59B-1C3B-4C85-A736-F19E6B59785BQ50084275-4229C52C-8953-4E2F-A5A6-6BF098018326Q57036570-4E5F1D89-E96D-4C42-B2B2-6938D880FE1AQ57255465-BB8E7C43-8EE2-4816-8D92-860661C501E6
P2860
Distance from sub-Saharan Africa predicts mutational load in diverse human genomes.
description
2015 nî lūn-bûn
@nan
2015年の論文
@ja
2015年論文
@yue
2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
@zh-tw
2015年论文
@wuu
2015年论文
@zh
2015年论文
@zh-cn
name
Distance from sub-Saharan Africa predicts mutational load in diverse human genomes.
@ast
Distance from sub-Saharan Africa predicts mutational load in diverse human genomes.
@en
type
label
Distance from sub-Saharan Africa predicts mutational load in diverse human genomes.
@ast
Distance from sub-Saharan Africa predicts mutational load in diverse human genomes.
@en
prefLabel
Distance from sub-Saharan Africa predicts mutational load in diverse human genomes.
@ast
Distance from sub-Saharan Africa predicts mutational load in diverse human genomes.
@en
P2093
P2860
P50
P356
P1476
Distance from sub-Saharan Africa predicts mutational load in diverse human genomes.
@en
P2093
Brenna M Henn
Brian K Maples
Howard Cann
Isabelle Dupanloup
Jeffrey M Kidd
Michael P Snyder
Mikhail Lipatov
Shaila Musharoff
P2860
P304
P356
10.1073/PNAS.1510805112
P407
P577
2015-12-28T00:00:00Z