Mutations on the DNA-binding surface of TATA-binding protein can specifically impair the response to acidic activators in vivo.
about
Transcription factor IIA mutations show activator-specific defects and reveal a IIA function distinct from stimulation of TBP-DNA bindingSPN1, a conserved gene identified by suppression of a postrecruitment-defective yeast TATA-binding protein mutantRNA polymerase subunit RPB5 plays a role in transcriptional activationThe Saccharomyces cerevisiae Srb8-Srb11 complex functions with the SAGA complex during Gal4-activated transcription.Impairment of the DNA binding activity of the TATA-binding protein renders the transcriptional function of Rvb2p/Tih2p, the yeast RuvB-like protein, essential for cell growth.Analysis of TFIIA function In vivo: evidence for a role in TATA-binding protein recruitment and gene-specific activation.Saccharomyces cerevisiae HMO1 interacts with TFIID and participates in start site selection by RNA polymerase II.Molecular genetics of the RNA polymerase II general transcriptional machineryComputer-based screening of functional conformers of proteins.Improved Tet-responsive promoters with minimized background expression.The yeast TAF145 inhibitory domain and TFIIA competitively bind to TATA-binding proteinThe Gcn4p activation domain interacts specifically in vitro with RNA polymerase II holoenzyme, TFIID, and the Adap-Gcn5p coactivator complex.TATA-binding protein mutants that increase transcription from enhancerless and repressed promoters in vivoA TATA binding protein mutant with increased affinity for DNA directs transcription from a reversed TATA sequence in vivo.Evidence for the involvement of the Glc7-Reg1 phosphatase and the Snf1-Snf4 kinase in the regulation of INO1 transcription in Saccharomyces cerevisiaeTranscriptional activation in yeast cells lacking transcription factor IIA.Multiple functions of the nonconserved N-terminal domain of yeast TATA-binding protein.TATA-binding protein mutants that are lethal in the absence of the Nhp6 high-mobility-group proteinDrosophila TAF(II)230 and the transcriptional activator VP16 bind competitively to the TATA box-binding domain of the TATA box-binding proteinConsiderations of transcriptional control mechanisms: do TFIID-core promoter complexes recapitulate nucleosome-like functions?Synergistic and promoter-selective activation of transcription by recruitment of transcription factors TFIID and TFIIB.Mechanism of differential utilization of the his3 TR and TC TATA elementsA new class of activation-defective TATA-binding protein mutants: evidence for two steps of transcriptional activation in vivo.Identification of seven hydrophobic clusters in GCN4 making redundant contributions to transcriptional activationA severely defective TATA-binding protein-TFIIB interaction does not preclude transcriptional activation in vivo.Identification of RTF1, a novel gene important for TATA site selection by TATA box-binding protein in Saccharomyces cerevisiae.Transcriptional activation by TFIIB mutants that are severely impaired in interaction with promoter DNA and acidic activation domains.TFIIA has activator-dependent and core promoter functions in vivo.Cisplatin- and UV-damaged DNA lure the basal transcription factor TFIID/TBP.Structural and functional analysis of mutations along the crystallographic dimer interface of the yeast TATA binding proteinA yeast TATA-binding protein mutant that selectively enhances gene expression from weak RNA polymerase II promoters.Transcription reinitiation rate: a special role for the TATA box.Critical role of the second stirrup region of the TATA-binding protein for transcriptional activation both in yeast and human.Mutations in the TATA-binding protein, affecting transcriptional activation, show synthetic lethality with the TAF145 gene lacking the TAF N-terminal domain in Saccharomyces cerevisiae.Mutations on the DNA binding surface of TBP discriminate between yeast TATA and TATA-less gene transcription.Compensatory energetic relationships between upstream activators and the RNA polymerase II general transcription machinery.Cooperative and competitive protein interactions at the hsp70 promoter.
P2860
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P2860
Mutations on the DNA-binding surface of TATA-binding protein can specifically impair the response to acidic activators in vivo.
description
1995 nî lūn-bûn
@nan
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
1995年论文
@zh
1995年论文
@zh-cn
name
Mutations on the DNA-binding s ...... to acidic activators in vivo.
@ast
Mutations on the DNA-binding s ...... to acidic activators in vivo.
@en
type
label
Mutations on the DNA-binding s ...... to acidic activators in vivo.
@ast
Mutations on the DNA-binding s ...... to acidic activators in vivo.
@en
prefLabel
Mutations on the DNA-binding s ...... to acidic activators in vivo.
@ast
Mutations on the DNA-binding s ...... to acidic activators in vivo.
@en
P2860
P356
P1476
Mutations on the DNA-binding s ...... to acidic activators in vivo.
@en
P2860
P304
P356
10.1128/MCB.15.10.5461
P407
P577
1995-10-01T00:00:00Z